Fig. 1

Negative correlation between miR-335 and BCL2L2 levels in ovarian cancer. A BCL2L2 levels in ovarian cancer tissues were significantly upregulated. B The levels of miR-335 in ovarian cancer tissues were significantly decreased. C, D miR-335 mimic was used to achieve overexpression of miR-335, while miR-335 inhibitor was used to achieve inhibition of miR-335 in SKOV3 and OVCAR3 cell lines. E, F miR-335 overexpression inhibited while miR-335 silence increased the expression of BCL2L2 in SKOV3 and OVCAR3 cell lines. *P < 0.05, **P < 0.01