Clinical factors | Training set (n = 156) | P | Validation set (n = 68) | Â | Â | ||
---|---|---|---|---|---|---|---|
HCC (n = 104) | FNH (n = 52) | HCC (n = 45) | FNH (n = 23) | P | P* | ||
Gender, male/female | 84/20 | 18/34 | 0.001 | 40/5 | 12/11 | 0.002 | 0.136 |
Age, ≤50/>50 years | 33/71 | 45/7 | 0.001 | 12/33 | 19/4 | 0.001 | 0.644 |
Hbsag, negative/positive | 21/83 | 38/14 | 0.001 | 16/29 | 16/7 | 0.016 | 0.252 |
AFP, ≤400/> 400 ng/ml | 99/5 | 52/0 | 0.261 | 45/0 | 23/0 | - | 0.317 |
MRI tumour number, single/multiple | 89/15 | 36/16 | 0.028 | 40/5 | 16/7 | 0.101 | 0.838 |
MRI tumour size, cm | 4.35 [2.60, 6.25] | 2.50 [1.90, 3.33] | 0.001 | 4.40 [3.00, 6.20] | 2.70 [2.05, 3.95] | 0.006 | 0.849 |
Liver steatosis, absent/present | 78/26 | 39/13 | 1.000 | 33/12 | 20/3 | 0.331 | 0.762 |
Liver haemangioma, absent/present | 88/16 | 49/3 | 0.141 | 42/3 | 22/1 | 1.000 | 0.235 |
Location, internal/subcapsular | 36/68 | 30/22 | 0.010 | 16/29 | 11/12 | 0.474 | 0.829 |
Margin, ill-defined/well-defined | 26/78 | 11/41 | 0.739 | 11/34 | 3/20 | 0.434 | 0.734 |
Shape, not round/round | 46/58 | 29/23 | 0.234 | 18/27 | 16/7 | 0.040 | 0.905 |
Pseudocapsule, absent/present | 67/37 | 28/24 | 0.270 | 24/21 | 13/10 | 1.000 | 0.448 |
Lesion homogeneity, Heterogeneous/homogeneous | 68/36 | 21/31 | 0.005 | 29/16 | 7/16 | 0.016 | 0.672 |
Lesion with steatosis, absent/present | 86/18 | 49/3 | 0.082 | 38/7 | 22/1 | 0.337 | 0.895 |
Central vascular supply, absent/present | 90/14 | 49/3 | 0.238 | 36/9 | 21/2 | 0.396 | 0.380 |
Central scar, absent/present | 82/22 | 37/15 | 0.387 | 40/5 | 14/9 | 0.017 | 0.734 |
Enhancement pattern | Â | Â | 0.001 | Â | Â | 0.001 | 0.56 |
 Early enhancement + washout | 82 | 15 | - | 36 | 7 | - | - |
 Early enhancement + no washout | 14 | 35 | - | 7 | 16 | - | - |
 Other patterns | 8 | 2 | - | 2 | 0 | - | - |