Fig. 2

Colorectal cancer cell migration and invasion were suppressed by miR-490-3p. a Three mimic sequences and inhibitor sequences were used, and the most effective inhibitor and mimics were selected in the following experiments. b The knockdown model of miR-490-3p in SW480 cell line and overexpressed model of miR-490-3p in LOVO cell line were established. c The cell migration and invasion of colorectal cancer cells were measured after LV-inhibitor treatment. d The cell migration and invasion of colorectal cancer cells were increased significantly after miR-490-3p was knockdown. e The cell migration and invasion of colorectal cancer cells were measured after LV-mimics treatment. f After treatment with LV-mimics, cell migration and invasion were remarkably suppressed