Table 2 Univariate analysis of long-term survival using Cox regression for each variable
Variables | Total N (%) 149 (100) | Alive 101 (67.8%) | Death 48 (32.2%) | P | HR (CI 95%) |
|---|---|---|---|---|---|
Age | |||||
Median (IQR) | 75 (72–80) | 74 (72–79) | 78 (73–80.75) | 0.140 | 1.03 (0.99–1.09) |
Gender | |||||
Men | 96 (64.4) | 61 (60.4) | 35 (72.9) | 0.074 | 0.56 (0.30–1.07) |
Women | 53 (35.6) | 40 (39.6) | 13 (27.1) | ||
ASA | |||||
I–II | 47 (31.5) | 36 (35.6) | 11 (22.9) | 0.241 | 1.50 (0.76–2.94) |
III–IV | 102 (68.5) | 65 (64.4) | 37 (77.1) | ||
Charlson Index | |||||
Median (IQR) | 3.0 (2.0–4.0) | 3.0 (2.0–3.0) | 3.0 (2.0–5.0) | 0.001* | 1.37 (1.17–1.60) |
Barthel | |||||
< 80 | 14 (9.4) | 8 (7.9) | 6 (12.5) | 0.314 | 0.64 (0.27–1.52) |
≥ 80 | 135 (90.6) | 93 (92.1) | 42 (87.5) | ||
Lawton-Brody | |||||
Median (IQR) | 6.0 (5.0–8.0) | 7.0 (5.0–8.0) | 6.0 (4.0–7.0) | 0.011* | 0.85 (0.76–0.97) |
Pfeiffer | |||||
< 3 | 140 (94.0) | 97 (96.0) | 43 (89.6) | 0.157 | 1.95 (0.77–4.94) |
≥ 3 | 9 (6.0) | 4 (4.0) | 5 (55.6) | ||
BMIa | |||||
Mean ± SD | 26.8 (± 4.0) | 26.7 (± 4.1) | 26.9 (± 3.7) | 0.938 | 1.00 (0.94–1.07) |
MNAb | |||||
Median IQR | 10.0 (9.0–12.0) | 10.0 (9.0–12.5) | 10.5 (9.0–12.0 | 0.588 | 0.97 (0.85–1.09) |
Frailty | |||||
No | 90(60.4) | 64 (63.4) | 26 (54.2) | 0.249 | 1.40 (0.79–2.47) |
Yes | 59 (39.6) | 37 (36.6) | 22 (45.8) | ||
Hemoglobin gr/dL | |||||
Mean (±SD) | 12.5 (± 2.2) | 12.6 (± 2.1) | 12.3 (± 2.3) | 0.703 | 0.98 (0.86–1.11) |
Creatinine mg/dL | |||||
Median (IQR) | 0.96 (0.79–1.13) | 0.94 (0.79–1.07) | 1.00 (0.80–1.33) | 0.060 | 1.66 (0.98–2.81) |
Albumin gr/dL | |||||
Mean (±SD) | 3.8 (± 0.5) | 3.8 (± 0.5) | 3.7 (± 0.5) | 0.430 | 0.749 (0.37–1.54) |
Laparoscopic approach | |||||
n (%) | 56 (38.9) | 41 (40.6) | 15 (31.3) | 0.118 | 0.635 (0.36–1.12) |
Anastomosis | |||||
No | 22 (14.8) | 10 (9.9) | 12 (25.0) | 0.024* | 0.47 (0.24–0.91) |
Yes | 127 (85.2) | 91 (90.1) | 36 (75.0) | ||
Transfusions | |||||
No | 116 (77.9) | 80 (79.2) | 36 (75.0) | 0.516 | 1.24 (0.65–2.39) |
Yes | 33 (22.1) | 21 (20.8) | 12 (25.0) | ||
T | |||||
1–2 | 45 (30.2) | 34 (33.7) | 11 (22.9) | 0.228 | 1.51 (0.77–2.97) |
3–4 | 104 (69.8) | 67 (66.3) | 37 (77.1) | ||
N | |||||
0 | 102 (68.5) | 76 (75.2) | 26 (25.5) | 0.005* | 2.27 (1.29–4.01) |
1 | 47 (31.5) | 25 (24.8) | 22 (45.8) | ||
M | |||||
0 | 142 (95.3) | 100 (99.0) | 42 (87.5) | < 0.001* | 6.21 (2.59–14.93) |
1 | 7 (4.7) | 1 (1.0) | 6 (12.5) | ||
TNM stage | |||||
I–II | 99 (66.4) | 74 (73.3) | 25 (52.1) | 0.004* | 2.29 (1.30–4.04) |
III–IV | 50 (33.6) | 27 (26.7) | 23 (15.4) | ||
Anastomosis dehiscence | |||||
No | 139 (93.3) | 97 (96.0) | 42 (87.5) | 0.013* | 2.95 (1.25–6.96) |
Yes | 10 (6.7) | 4 (4.0) | 6 (12.5) | ||
Chemotherapy | |||||
No | 112 (75.2) | 75 (74.3) | 37 (77.1) | 0.890 | 0.95 (0.49–1.87) |
Yes | 37 (24.8) | 26 (25.7) | 11 (22.9) | ||