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Table 1 The differences between fast-track and the conventional surgical procedures for colorectal cancer

From: Retrospective analysis of safety and efficacy of enhanced recovery pathways in stage II–III colorectal cancer patients submitted to surgery and adjuvant therapy

Parameters

Fast-track surgical procedure

The conventional surgical procedure

Preadmission

Mental optimism.

No mental optimism.

Counseling

Pre-assessment for risk adjustment.

Pre-assessment for risk adjustment.

Information for thoracic epidural and general combined anesthesia.

No information for combined anesthesia.

Information for fast-track surgical procedure and consent.

Information for the conventional surgical procedure and consent.

Surgical preparation

Bowel preparation.

Bowel preparation.

Enemas.

Enemas.

The last meal: 2 h before surgery.

The last meal: 10 h before surgery.

Complete enteral nutritional. 500 mL 10% glucose 2–3 h before surgery (if required).

No oral intake on the day of surgery.

Gastrointestinal decompression

~30 min before surgery by the nasogastric tube.

~30 min before surgery by the nasogastric tube.

Perioperative management

Thoracic epidural anesthesia.

No thoracic epidural anesthesia.

Balanced combination with the general anesthesia.

Normal general anesthesia.

Mechanical ventilation.

Mechanical ventilation.

General anesthesia

Propofol and rocuronium

Propofol and rocuronium

Opioid

Morphine injection as low as possible.

No restriction of morphine injection use.

Monitoring

Hemodynamic parameters.

Hemodynamic parameters.

Prophylaxis

Intravenous antibiotic(s).

Intravenous antibiotic(s).

Surgery

Laparoscopy/open surgical procedure.

Laparoscopy/open surgical procedure.

Warming

Yes.

No.

Drains

Minimal use.

Regular use.

Fluid infusion

≤ 1.5 L.

No restriction.

Pain management

Epidural analgesia + paracetamol infusion.

Sufentanil.

Postoperative diet

1-piece chewing gum three times in a day (if required).

Chewing gum.

200 mL 10% glucose within 1 day after operation (if required).

Fasting until flatus.

Liquid diet on the next day of operation (if required).

Liquid diet after flatus.

The rehabilitation of diet as early as possible.

Diet after defecation.

Intravenous fluid infusion

Maximum for 3 days or until nutritional emulsion administered

High energy fluid on daily basis (infusion) until oral intake.

Energy

25–30 kcal/kg/day.

25–30 kcal/kg/day.

Nasogastric tube

Removed after surgery.

Removed after the first flatus.

Urethral catheter

Removed within 2 days after surgery.

Removed when automatic micturition feeling.

Ambulation

Within 24 h after surgery, ≥ 1 h/day and gradually increased.

No ambulation schemes.

Adjuvant chemotherapy (if required; institutional protocol)

8 cycles of capecitabine and oxaliplatin; every 21 days

12 cycles of leucovorin, fluorouracil, and oxaliplatin; every 15 days

Hospitalization for chemotherapy

1 day

3 days

  1. All surgical procedures were performed according to the National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology® Colon Cancer V.2.2018.