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Table 1 Age, gender, pathological diagnosis, treatment, and outcome in patients with primary sacral lymphoma reported in literature till December 2020

From: Primary sacral non-Hodgkin’s lymphoma: report of a case and systematic review of literature

Author and year [Ref]

Age

Gender

Histology

Treatment

Follow-up

Outcome

Nayil K et al. 2011 [9]

56

M

NHL-B cell no further categorization

S1-S2 laminectomy + RT

6 months

Well

Shimada A et al. 2013 [10]

85

M

Non GC type DLBCL, EBV, Myc translocation

R-CHOP

12 months

CR, disease free

Xu T et al. 2020 [13]

84

F

DLBCL

R-CHOP

5 months

CMR

Li GN et al. 2020 [6]

77

M

DLBCL

R-CHOP

1 month

On therapy

Ediriwickrima LS and Zaheer W 2011 [5]

67

M

DLBCL with lupus anticoagulant

R-CHOP

2 months

Disappearance of lupus anticoagulant

Wang J et al. 2020 [19]

35 cases Mean 46.2 years

15 M

20 F

Lymphoma (NOS)

Not described

Not described

NR

Liu JK et al. 2003 [7]

52

M

DLBCL

S2-S3 sacral laminectomy+ RCHOP + RT

4 months

Reduction in size, no metabolic imaging performed

Liu JK et al. 2003 [7]

64

M

DLBCL

3 cycles of CHOP followed by RT

13 months

Reduction in size, no metabolic imaging performed

Thornton E et al 2012 [20]

53

M

Lymphoma (NOS)

Not reported

Not reported

Not reported

Fourati N et al. 2017 [21]

24

HD

BEACOPP ×2

ABVD ×4

RT

15 months

CR

Ha-Ou-Nou F et al 2013 [22]

35

M

HD

ABVD

NR

NR

Ezenekwe AM et al 2004 [23]

50

M

Precursor B cell lymphoblastic lymphoma

Carmustine, cyclophosphamide, cytarabine, doxorubicin, etoposide followed by surgical excision

10

CR

Loh JK et al. 2005 [24]

6

M

Lymphoma (NOS)

Subtotal resection

11 years

CR

Hermann G et al. 1997 [25]

NR

NR

Lymphoma (NOS)

NR

NR

NR

Theodorou DJ et al 2000 [12]

58

M

Monostotic primary non-Hodgkin’s lymphoma of the bone with intrathecal involvement

Combination chemo

Intrathecal MTX

RT

Peripheral blood stem cell transplant

1 year

CR

Chaari N et al. 2011 [4]

49

F

DLBCL

NR

NR

NR

Kirsch DG et al. 2005 [26]

14

F

HD

Two cycles of vincristine, prednisone, procarbazine, and doxorubicin followed by four cycles of cyclophosphamide, vincristine, prednisone, procarbazine + proton beam RT

2.5 years

CR

Ackerman L et al. 1994 [27]

36

M

Large cell lymphoma

NR

NR

NR

Tazi EM et al. 2009 [11]

45

M

DLBCL

CHOP +RT

10 years

CR, later developed histoplasmosis at same site

Amonkar AP et al. 2017 [3]

39

M

GC type DLBCL

RT followed by CHOP

NR

NR

Mally R et al. 2011 [8]

24

M

DLBCL

CHOP

Intrathecal MTX

RT

3 months

NR

Present case

36

M

DLBCL

RCHOP

Maintenance R

RT

36 months

CR

  1. CR Complete response, CMR Complete metabolic response, NR Not reported, HD Hodgkin's disease, GC germinal center, DLBCL Diffuse large B cell lymphoma