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Table 1 Demographics of the included studies comparing 2D and 3D ET

From: Comparison between 3-dimensional and 2-dimensional endoscopic thyroidectomy for benign and malignant lesions: a meta-analysis

First author/year

City/country

Study type

NOS stars/Jadad score

3D VS. 2D

Diseases/surgical approach

3D system

No. of participants

Gender (male/female, n)

Mean age (year)a

Tang Tao, 201 9[15]

Sichuan, China

RS

7★/−

32

36

2/30

1/35

39.25 ± 8.73

41.72 ± 7.94

Thyroid cancer/via breast approach

NR

Chen Jian, 2015 [16]

Hubei, China

RS

8★/−

26

34

6/20

6/28

46.15 ± 11.74

49.29 ± 11.61

Thyroid diseases/via modified chest and mammary areola approach

NR

Liu Xue-Wen, 2017 [17]

Guangdong, China

RS

7★/−

30

30

5/25

4/26

41.40 ± 9.07

40.93 ± 7.65

Thyroid cancer/via breast approach

NR

Huang Jue, 2020 [18]

Henan, China

RCT

−/3

32

32

7/25

10/22

55.27 ± 6.34

56.81 ± 7.10

Thyroid cancer/via breast approach

Olympus Corporation,

Japan

Jiang Yinhai, 2019 [19]

Shandong, China

RS

8★/−

40

40

6/34

7/33

41.10 ± 6.80

43.10 ± 7.20

Thyroid cancer/via breast approach

Viking 3D HD system, USA

Feng Jianping, 2020 [20]

Guangdong, China

RS

8★/−

26

25

4/22

2/23

30.27 ± 7.95

31.44 ± 6.97

Thyroid cancer/via breast approach

Viking 3D HD system, USA

Xing Ying, 2018 [21]

Beijing, China

RCT

−/3

42

42

10/32

8/34

47.60 ± 8.50

49.30 ± 9.50

Thyroid cancer/via modified chest and mammary areola approach

NR

Zou Zhaowei, 2014 [22]

Guangdong, China

RS

7★/−

30

30

10/20

12/18

43.30 ± 7.81

44.40 ± 7.59

Benign thyroid nodules/via breast approach

NR

Jiasheng Xu, 2018 [23]

Jiangxi, China

RS

7★/−

88

92

NR

NR

29.51 ± 5.36

34.36 ± 5.53

Benign thyroid nodules/via breast approach

NR

Zi-Fang Zheng, 2018 [24]

Fujian, China

RS

7★/−

50

50

12/38

15/35

36.70 ± 7.50

37.30 ± 7.80

Thyroid diseases/via the trans-thoracoareolar approach

Karl Storoz, Germany

Zhao Bei-yong, 2020 [25]

Henan, China

RCT

−/3

69

69

7/62

9/60

36.85 ± 7.11

36.21 ± 6.97

Benign thyroid nodules/via breast approach

NR

Li Dongwei, 2018 [26]

Guangdong, China

RS

8★/−

26

35

3/23

5/30

34.60 ± 9.00

35.50 ± 9.20

Benign thyroid nodules/via breast approach

Olympus Corporation,

Japan

Fan Dunhui, 2019 [27]

Gansu, China

RS

7★/−

35

35

19/16

20/15

41.16 ± 5.02

40.25 ± 4.56

Benign thyroid nodules/via breast approach

Karl Storoz, Germany

Li Weiqi, 2017 [28]

Guangdong, China

RCT

−/3

20

20

5/15

6/14

43.10 ± 7.20

40.70 ± 8.00

Benign thyroid nodules/via breast approach

Karl Storoz, Germany

Zhang Duojun, 2017 [29]

Neimenggu, China

RS

7★/−

37

37

4/33

7/30

36.25 ± 5.28

37.2 ± 7.12

Benign thyroid nodules/via breast approach

Olympus Corporation, Japan

  1. NOS Nottingham-Ottawa scale, 3D 3-dimensional, 2D 2-dimensional, RS retrospective study, RCT randomized controlled trial, NR not reported, ET endoscopic thyroidectomy
  2. aData are the mean ± standard deviation
  3. ★ Number of stars for Nottingham-Ottawa scale for each included trial