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Table 4 Univariate and multivariate analysis of risk factors associated with postoperative complications in patients with gastric cancer undergoing laparoscopic surgery

From: Preoperative Controlling Nutritional Status (CONUT) score predicts short-term outcomes of patients with gastric cancer after laparoscopy-assisted radical gastrectomy

Characteristics

Postoperative complications (N = 91)

No postoperative complications (N = 218)

P value

Multivariate

OR

95% CI

P value

Age, year

68.2 ± 1.1

61.4 ± 0.7

< 0.001

2.237

1.048-4.774

0.037

Gender

 Male

70 (76.9)

158 (72.5)

0.418

   

 Female

21 (23.1)

60 (27.5)

0.418

   

BMI, kg/m2

22.2 ± 0.3

23.0 ± 0.2

0.059

   

Comorbidities

 Diabetes mellitus

14 (15.4)

24 (11.0)

0.286

   

 Hypertension

39 (42.9)

78 (35.8)

0.242

   

History of abdomen surgery

20 (22.0)

50 (22.9)

0.855

   

Preoperative laboratory measurements

 Hb, g/L

113.6 ± 2.9

128.2 ± 1.4

< 0.001

0.521

0.219-1.237

0.139

 CRP, mg/L

9.0 ± 1.8

3.5 ± 0.6

< 0.001

1.193

0.500-2.849

0.691

 WBC, ×109/L

5.85 ± 0.19

5.88 ± 0.11

0.881

   

 RBC, ×1012/L

3.78 ± 0.08

4.29 ± 0.04

< 0.001

0.356

0.180-0.707

0.003

 Platelets, ×109/L

216.0 ± 7.5

217.2 ± 4.5

0.887

   

CONUT score

3.7 ± 0.3

1.6 ± 0.1

< 0.001

2.433

1.218-4.862

0.012

 Albumin, g/L

36.4 ± 0.6

40.1 ± 0.3

< 0.001

   

 Total lymphocytes, ×109/L

1.33 ± 0.06

1.66 ± 0.05

< 0.001

   

 Cholesterol, mmol/L

4.20 ± 0.13

4.77 ± 0.07

< 0.001

   

Preoperative tumour biomarkers

 CA125, u/ml

15.5 ± 1.4

12.8 ± 1.0

0.129

   

 CA199, u/ml

38.7 ± 13.5

23.3 ± 3.2

0.126

   

 CEA, ng/ml

6.2 ± 1.5

5.6 ± 2.2

0.869

   

 AFP, μg/L

22.5 ± 19.4

3.3 ± 0.3

0.128

   

Types of operative procedure

   

1.345

0.740-2.444

0.331

 Distal gastrectomy

49 (53.8)

144 (66.1)

0.043

   

 Total gastrectomy

42 (46.2)

74 (33.9)

0.043

   

Intraoperative fluid utilisation, ml

2082 ± 66.6

2195 ± 42.1

0.148

   

Operative time, min

272.7 ± 5.3

271.5 ± 3.7

0.853

   

Estimated blood loss, ml

124.2 ± 11.8

98.5 ± 9.1

0.110

   

T factor

 T1

14 (15.4)

77 (35.3)

< 0.001

1.131

0.353-3.622

0.836

 T2

8 (8.8)

27 (12.4)

0.364

   

 T3

16 (17.6)

26 (11.9)

0.186

   

 T4

53 (58.2)

88 (40.4)

0.004

1.402

0.643-3.058

0.396

N factor

 N0

25 (27.5)

93 (42.7)

0.012

2.596

0.810-8.317

0.108

 N1

14 (15.4)

30 (13.8)

0.710

   

 N2

10 (11.0)

43 (19.7)

0.063

   

 N3

42 (46.2)

52 (23.9)

< 0.001

1.903

0.936-3.868

0.075

pTNM stage

 I

19 (20.9)

83 (38.1)

0.003

1.141

0.302-4.311

0.846

 II

10 (11.0)

41 (18.8)

0.092

   

 III

60 (65.9)

88 (40.4)

< 0.001

2.897

0.986-8.511

0.053

 IV

2 (2.2)

6 (2.8)

0.780

   

Postoperative stay, days

20.7 ± 1.4

10.2 ± 0.2

< 0.001

   
  1. Values in parentheses are percentages unless indicated otherwise; the other values are mean ± Sd
  2. BMI body mass index; Hb haemoglobin; CRP C-reactive protein; WBC white blood cells; RBC red blood cells; CONUT Controlling Nutritional Status
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World Journal of Surgical Oncology

ISSN: 1477-7819

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