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Table 2 Study population and baseline characteristics of the patients sorted by the CONUT score

From: Preoperative Controlling Nutritional Status (CONUT) score predicts short-term outcomes of patients with gastric cancer after laparoscopy-assisted radical gastrectomy

Characteristics

All (N = 309)

CONUT< 2.5 (N = 214)

CONUT> 2.5 (N = 95)

P value

Age, years

63.4 ± 0.6

62.2 ± 0.7

66.2 ± 1.2

0.003

Gender

   

0.416

 Male

228 (73.8)

155 (72.4)

73 (76.8)

 

 Female

81 (26.2)

59 (27.6)

22 (23.2)

 

BMI, kg/m2

22.8 ± 0.2

23.1 ± 0.2

21.9 ± 0.3

< 0.001

Comorbidities

 Diabetes mellitus

38 (12.3)

19 (8.9)

19 (20.0)

0.006

 Hypertension

117 (37.9)

76 (35.5)

41 (43.2)

0.201

History of abdomen surgery

70 (22.7)

40 (18.7)

30 (31.6)

0.013

Preoperative laboratory measurements

 Hb, g/L

123.9 ± 1.4

132.5 ± 1.3

104.5 ± 2.4

< 0.001

 Albumin, g/L

39.0 ± 0.3

40.9 ± 0.3

34.6 ± 0.5

< 0.001

 CRP, mg/L

5.2 ± 0.7

3.2 ± 0.6

9.6 ± 1.8

< 0.001

 WBC, × 109/L

5.87 ± 0.09

5.99 ± 0.10

5.61 ± 0.21

0.064

 RBC, × 1012/L

4.14 ± 0.04

4.38 ± 0.04

3.60 ± 0.07

< 0.001

 Platelets, × 109/L

216.8 ± 3.8

221.4 ± 4.5

206.5 ± 7.4

< 0.001

 Total lymphocytes, × 109/L

1.56 ± 0.04

1.79 ± 0.04

1.04 ± 0.04

< 0.001

 Cholesterol, mmol/L

4.60 ± 0.06

5.02 ± 0.07

3.64 ± 0.08

< 0.001

Preoperative tumour biomarkers

 CA125, u/ml

13.6 ± 0.8

11.8 ± 0.9

17.4 ± 1.7

0.001

 CA199, u/ml

27.9 ± 4.6

20.4 ± 2.8

43.9 ± 13.0

0.016

 CEA, ng/ml

5.8 ± 1.6

6.1 ± 2.3

5.1 ± 1.2

0.769

 AFP, μg/L

8.9 ± 5.8

11.7 ± 8.4

3.0 ± 0.5

0.487

Types of operative procedure

   

0.498

 Distal gastrectomy

193 (62.5)

131 (61.2)

62 (65.3)

 

 Total gastrectomy

116 (37.5)

83 (38.8)

33 (34.7)

 

Intraoperative fluid utilisation, ml

2161 ± 35.7

2209 ± 41.1

2042 ± 69.4

0.034

Operative time, min

271.8 ± 3.0

273.4 ± 3.6

268.4 ± 5.8

0.444

Estimated blood loss, ml

106.1 ± 7.3

103.0 ± 9.3

112.9 ± 11.2

0.531

T factor

 T1

91 (29.4)

78 (36.4)

13 (13.7)

< 0.001

 T2

35 (11.3)

22 (10.3)

13 (13.7)

0.384

 T3

42 (13.6)

23 (10.7)

19 (20.0)

0.029

 T4

141 (45.6)

91 (42.5)

50 (52.6)

0.100

N factor

 N0

118 (38.2)

94 (43.9)

24 (25.3)

0.002

 N1

44 (14.2)

30 (14.0)

14 (14.7)

0.868

 N2

53 (17.2)

38 (17.8)

15 (15.8)

0.672

 N3

94 (30.4)

52 (24.3)

42 (44.2)

< 0.001

pTNM stage

 I

102 (33.0)

80 (37.4)

22 (23.2)

0.014

 II

51 (16.5)

41 (19.2)

10 (10.5)

0.059

 III

148 (47.9)

88 (41.1)

60 (63.2)

< 0.001

 IV

8 (2.6)

5 (2.3)

3 (3.2)

0.975

Postoperative stay, days

13.6 ± 0.5

11.6 ± 0.5

14.1 ± 0.7

0.006

Postoperative complications

91 (29.4)

41 (19.2)

50 (52.6)

< 0.001

  1. Values in parentheses are percentages unless indicated otherwise; the other values are mean ± Sd
  2. BMI body mass index; Hb haemoglobin; CRP C-reactive protein; WBC white blood cells; RBC red blood cells
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World Journal of Surgical Oncology

ISSN: 1477-7819

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