Table 3 Validation of 7 differentially methylated genes through mixed cohort 2, including breast cancer (GSE72254) and normal tissues (GSE74214, GSE141338, GSE100850)
Gene | Case, N | Control, N | Specificity (%) | Sensitivity (%) | Accuracy (%) |
|---|---|---|---|---|---|
ADCY4 | 58 | 29 | 62.07 | 87.93 | 79.31 |
CPXM1 | 58 | 29 | 72.41 | 79.31 | 77.01 |
DNM3 | 58 | 29 | 58.62 | 62.07 | 60.92 |
GNG4 | 58 | 29 | 93.10 | 63.79 | 73.56 |
MAST1 | 58 | 29 | 75.86 | 100.00 | 91.95 |
PRDM14 | 58 | 29 | 89.66 | 86.21 | 87.36 |
ZNF177 | 58 | 29 | 89.66 | 93.10 | 91.95 |