Table 4 Anatomical pathology findings comparison between TA (group A) and APA (group B)

Single gland disease

100 (93.5)

10 (100.0)

1.000

Double typical adenoma

7 (6.5)

0(0.0)

1.000

Size of parathyroid gland (mm) ^a

23 ± 13

25 ± 30

0.001

Weight of parathyroid gland (mg)

40 ± 16

120 ± 64

<  0.001

Clinical/intraoperative adherence

0 (0.0)

0 (0.0)

–

Pseudocapsular invasion

0 (0.0)

4 (40.0)

<  0.001

Bands of fibrosis

4 (3.7)

5 (50.0)

< 0.001

Pronounced trabecular growth

7 (6.5)

6 (60.0)

< 0.001

Mitotic rates of > 1/10 HPFS

2 (1.9)

6 (60.0)

< 0.001

Tumor necrosis^b

0 (0.0)

1 (10.0)

0.085

Nuclear pleomorphism

2 (1.9)

2 (20.0)

0.036

Cystic degeneration

8 (7.5)

2 (20.0)

0.204

Thick capsule

0 (0.0)

4 (40.0)

< 0.001

Hemosiderin deposition

3 (2.8)

2 (20.0)

0.058

Hematic extravasion

5 (4.7)

2 (20.0)

0.110

Ki-67+ < 1%

11 (10.3)

0 (0.0)

0.598

Ki-67+ > 4%

0 (0.0)

4 (40.0)

< 0.001

Galactin-3 +

22 (20.6)

7 (70.0)

0.002

PGP 9.5 +

13 (12.1)

4 (40.0)

0.038