Fig. 4

miR-192 regulated RB1 expression in NPC. a miR-192 has a binding site with the 3′-UTR of RB1. b Dual-luciferase reporter assays were performed to investigate the effects of miR-192 on the 3′-UTR of RB1 activity. c The negative correlation between miR-192 and RB1 expressions was found in NPC tissues (n = 28) using Spearman correlation analysis. d, e RB1 expression was detected in C666-1 cells with miR-192 mimics or inhibitor using RT-qPCR and Western blot analysis. **P < 0.01