Skip to main content

Table 1 Demographics and clinical characteristics of CPM patients undergoing CRS and HIPEC

From: The importance of synchronicity in the management of colorectal peritoneal metastases with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

 All CPM (n = 102)s-CPM (n = 20)m-CPM (n = 82)p value
Patient characteristics
 Age, years54.0 (24–78)49 (24–72)55 (30–78)0.132
 Gender   1.000
  Male39 (38.2%)8 (40%)31 (37.8%) 
  Female63 (61.8%)12 (60%)51 (62.2%) 
 Race   0.004
  Chinese85 (82.5%)12 (60.0%)73 (89.0%) 
  Others17 (17.5%)8 (40.0%)9 (11.0%) 
 ECOG status   0.350
  0/194 (92.2%)20 (100.0%)74 (90.2%) 
  28 (7.8%)0 (0.0%)8 (9.8%) 
Tumour characteristics
 T-stage (primary tumour)   0.502
  T1–23 (2.9%)0 (0.0%)3 (3.7%) 
  T3–499 (97.1%)20 (100%)79 (96.3%) 
 N-stage (primary tumour)   0.15
  N0–163 (61.8%)11 (55%)52 (63.4%) 
  N231 (30.4%)6 (30%)25 (30.4%) 
  Unknown8 (7.8%)3 (15%)5 (6.2%) 
 Tumour differentiation (primary tumour)   1.02
  Well5 (5%)1(5%)4 (4.8%)
  Moderate60 (58.8%)10 (50%)50 (61%)
  Poor31 (30.4%)7(35%)24 (29.3%)
  Unknown6 (5.8%)2 (10%)4 (4.9%)
 Histology (primary tumour)   0.51
  Adenocarcinoma74 (72.5%)13 (65.0%)61 (74.5%)
  Mucinous23 (22.5%)6 (30.0%)17 (20.7%)
  Signet ring cell2 (2%)0 (0.0%)2 (2.4%)
  Mixed2 (2%)1 (5.0%)1 (1.2%)
  Others1 (1%)0 (0.0%)1 (1.2%)
 Sidedness of Tumour (primary tumour)   0.54
  Right32 (31.4%)7 (35%)25 (30.5%)
  Left51 (50%)10 (50%)41 (50%)
  Rectum15 (14.7%)1 (5%)14 (17%)
  Unknown4 (3.9%)2 (10%)2 (2.5%)
 Pre-operative CEA levels, mean (μG/l)32.343.1 (1.1 - 501)29.8 (0.5 – 441)0.043
Intra-operative
 PCI score, median (range)7 (0–27)9 (3–27)5 (0–24)0.12
 PCI score   0.11
  < 1055 (54%)10 (50%)45 (54.9%)
  10–2031 (30.3%)4 (20%)27 (32.9%)
  > 205 (5%)3 (15%)2 (3.8%)
  Unknown11 (10.7%)3 (15%)8 (8.4%)
 CC-score   0.352
  CC0101 (98.1%)19 (95.0%)82 (100%)
  CC11 (1.0%)1 (5.0%)0 (0.0%)
  1. PCI Peritoneal Cancer Index, CC-score Completeness of Cytoreduction Score