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Table 1 Demographic and clinical characteristics of treated patients

From: Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms

Characteristics

Overall patients, n (%)

Adverse events

G1–2, n

G3–4, n

Age (years)

Range

25-78

45–74

25–78

Median

56

61.5

53

 ≤ 56

50(48.1)

9

44

 > 56

54(51.9)

17

29

Gender

 Male

55(52.8)

19

34

 Female

49(47.1)

7

39

Smoking status

 Smoker

8(7.6)

2

5

 Non-smoker

96(92.3)

24

68

Alcohol intake

 Yes

4(3.8)

2

2

 No

100(96.1)

24

71

Anatomic site

 Rectum

39(37.5)

11

27

 Colon

65(62.5)

15

46

Histopathological type

 Adenocarcinoma

104(100.0)

26

73

 Squamous cell carcinoma

0(0)

0

0

 Adenocarcinoma histology

 Poorly differentiated

1(1)

0

1

 Moderately differentiated

57(54.8)

13

42

 Mucinous adenocarcinoma

3(2.9)

0

3

 Undefined

43(41.3)

13

27

Grade of tumor

 I

0(0)

0

0

 II

30(28.8)

6

22

 III

46(44.2)

15

31

 IV

28(27)

5

20

Clinical T-stage

 1

2(1.9)

0

2

 2

3(2.9)

1

2

 3

65(62.5)

19

44

 4

34(32.7)

6

25

Clinical N-stage

 0

33(31.7)

7

24

 1

42(40.4)

12

30

 2

28(26.9)

7

18

 3

1(1)

0

1

Clinical M-stage

 0

76(73)

21

53

 1

28(27)

5

20