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Table 4 Complete response of DLM

From: Imaging in disappearing colorectal liver metastases and their accuracy: a systematic review

Ref. Patients with DLM (%) Initial CRLM DLM DLM/patient CPR/resected DLM CCR/DLM left in situ Time to recurrence Median follow-up (months) DLM with CR DLM with CR + IOUS
Elias et al. [14] 15 (14) n.s. n.s. n/a n/a 8/11 patients 5, 5, 8 months 31 n/a n/a
Benoist et al. [13] 38 (7) 183 66 1.7 3/15 8/31 n.s. 12 17% 24%
Elias et al. [15] 16 (7) 134 69 4.3 n/a 10/16 patients n.s. 50 n/a n/a
Auer et al. [16] 39 (9) 166 118 3 44/68 31/50 Mean 21 months 41 64% 65%
Tanaka et al. [17] 23 (37) 472 86 3.7 6/17 16/27 Median 14 months 44 69% 80%
Goèré et al. [18] 27 (n/a) 523 96 3.6 n/a 18/27 Median 14 months 55 n/a n/a
van Vledder et al. [19] 40 (24) n.s 127 3.2 26/67 24/45 n.s. 20 45% 54%
Ferrero et al. [20] 33 (19) 624 67 2 22/57 4/10 Within 12 months n.s. 39% 64%
Park et al. [21] 87 (n/a) 393 CT: 203, MRI: 55 0.6 (MRI) CT: 47/168, MRI: 28/39 CT: 24/35, MRI: 15/16 Within 12 months 12 CT: 35%, MRI: 78% CT: 69%, MRI: 94%
Kim et al. [22] 43 (31) 289 168 3.9 8/8 128/150 n.s. 22 85% n/a
Arita et al. [23] 11 (15) 234 32 0.4 10/37 4/7 n.s. n.s. 41% IOUS: 46%, CE-IOUS: 75%
Owen et al. [24] 11 (48) 200 77 7 10/36 20/41 n.s. 46 40% n/a
Tani et al. [9] 20 (24) 619 111 5.6 CT: 54/78, MRI: 24/29 CT: 11/33, MRI: 16/18 Median 8 months 27 CT: 59%, +MRI: 85% 86%
Sturesson et al. [25] 29 (16) 141 66 2.3 24/56 3/4 n.s. n.s. 45% 96%
Oba et al. [8] 59 (32) 764 275 4.7 103/233 36/42 n.s. 27 CT: 51%, +MRI: 65% 92%
  1. DLM disappearing liver metastases, CRLM colorectal liver metastases, CPR complete pathological response, CCR complete clinical response, CR complete response, n.s. not stated, n/a not applicable, IOUS intraoperative ultrasound, CE-CT contrast-enhanced computed tomography, MRI magnetic resonance imaging, EOB-MRI gadoxetic acid-enhanced magnetic resonance imaging, CE-IOUS contrast-enhanced intraoperative ultrasound