Skip to main content

Table 2 Summary of operative treatment of outcomes of hepatic epithelioid hemangioendothelioma with survival data in reviewed literatures

From: Laparoscopic resection of hepatic epithelioid hemangioendothelioma: report of eleven rare cases and literature review

Author (year) No. Diagnostic methods Tumor size, mean, cm Metastasis Operative approach Recurrence rate, % Survival, %
Konstantinidis et al. (2018) [1] 67   14.8 NA LR or LT NA 83.4 (5-year)
Lai et al. (2017) [2] 149 Percutaneous and/or surgical biopsy NA Lung, breast LT and adjuvant therapy 24.8% 81 (5-year)
Dong et al. (2015) [3] 3 Liver biopsy NA NA LR and RFA, or LT 0 100 (3-year)
Remiszewski et al. (2014) [4] 10 Liver biopsy during diagnostic laparoscopy 5.1 Lymph node metastases LT 0 90 (5-year)
Noh et al. (2020) [5] 19 Liver biopsy 3.53 NA LR, LR + chemotherapy, LT + radiation therapy, LT + chemotherapy NA 88 (5-year)
Wang et al. (2018) [6] 1 Liver biopsy 4.7 No LR + chemotherapy 0 100 (15-year)
Sanduzzi-Zamparelli et al. (2020) [7] 11 Surgical specimens, needle biopsy or “wedge-biopsy”   Lung, Lymph node metastases LR or LT 36.4 100 (5-year)
Orlando et al. (2013) [8] 108 Percutaneous needle, surgical, or combined biopsies NA Osseous and peritoneal localizations LT NA 72 (5-year)
Jung et al. (2016) [9] 6 Liver biopsy NA NA HR or LT 16.7 83.3 (5-year)
Abdoh et al. (2016) [10] 1 Liver biopsy NA Intrahepatic metastasis LT 100 0 (1-year)
Theodosopoulos et al. (2013) [11] 5 Liver biopsy 4 Intrahepatic metastasis Surgical resection with a non-formal hepatectomy or wedge resection. 40 60 (2-year)
Grotz et al. (2010) [12] 22 Liver biopsy NA Lung, peritoneum, bone, brain and skin LR or LT 40 62 (LR, 5-year), 46 (LT, 5-year)
Wang et al. (2012) [13] 21 Surgical specimens NA Lung metastases, diaphragm/abdominal-wall metastases LR, LR followed by TACE,or LT NA 74.1 (LR, 3-year), 33.3 (LR followed by TACE, 3-year), 0 (LT, 3-year),
Thomas et al. (2012) [14] 7 Liver biopsy, diagnostic laparoscopy, surgical specimens 3.6 Lung Hepatectomy or LT 43 83 (5-year)
Krasnodębski et al. (2020) [15] 18 Liver biopsy NA Hilar lymph nodes LT 0 41.3 (5-year)
Thin et al. (2010) [16] 1 Liver biopsy NA Intrahepatic metastasis LT 0 100 (5-year)
Lin et al. (2015) [17] 1 Surgical specimens NA No LT 0 100 (5-year)
Samuk et al. (2016) [18] 1 Liver biopsy NA Lung LT 0 100 (5-year)
Sundar et al. (2015) [19] 11 Liver biopsy NA NA LT NA 78.7 (5-year)
Groeschl et al. (2014) [20] 12 Liver biopsy, surgical specimens NA NA Segmental resection, lobectomy/extended resection, LT NA 57 (LR, 1-year), 80 (LT, 1-year),
  1. LR liver resection, LT liver transplantation, RFA radiofrequency ablation, HR hepatic resection, TACE transcatheter arterial chemoembolization, NA not available