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Table 2 Clinicopathological characteristics of included studies

From: Laparoscopic procedure is associated with lower morbidity for simultaneous resection of colorectal cancer and liver metastases: an updated meta-analysis

Study Intervention Location of primary tumor (colon/rectum) Primary tumor size, mean
(SD), cm
No. of CRLM, mean (SD) CRLM
location (unilober/bilobar)
CRLM size R0 rate
(liver/colorectum)
Neoadjuvant therapy Mortality Conversions
Ma et al. [23] Lap 7/5 NR 1.6 (0.9) 7/5 3.73 ± 2.91 100/100 3 (25) 0 0
Open 7/5 NR 3.1 (1.8) 5/2 3.02 ± 1.62 100/100 3 (25) 0  
Ivanecz et al. [20] Lap 4/6 NR 1.4 (0.9) 9/1 2.0  ± 1.2 100/100 7 (70) 0 0
Open 6/4 NR 1.4 (0.9) 9/1 2.9 ± 1.5 100/100 3 (30) 0  
Xu et al. [26] Lap 15/5 3.2 (1.0) 6a 18/2 2.99 ± 1.55 100/100 6 (30) 0 0
Open 15/5 3.8 (1.2) 6 17/3 3.19 ± 1.53 100/100 4 (20) 0  
Chen et al [16]. Lap NR/NR 4.0 (2.0) 4a NR 5.5 ± 4.2 NR/NR NR 0 1
Open NR/NR 5.0 (3.0) 3 NR 4.7 ± 3.7 NR/NR NR 0  
Gorgun et al. [17] Lap 6/8 3.7 (0.7) 1.6 (0.3) 12/2 2.4 ± 0.7 86/NR 6 (43) 0 0
Open 14/15 3.7 (0.5) 2.1 ± 0.2 19/10 2.7 ± 0.2 93/NR 19 (66) 1  
Ratti et al [24]. Lap 13/12 NR 2.40 ± 1.27 13/12 3.65 ± 2.67 96/100 20 (80) 0 1
Open 27/23 NR 2.35 ± 1.34 27/23 3.94 ± 2.47 98/98 39 (78) 0  
Tranchart et al. [25] Lap 48/41 NR 1.4 ± 0.6 78/11 2.9  ± 1.9 83/NR 11 (12) 2 6
Open 51/38 NR 1.5 ± 0.7 81/8 2.8  ± 2.0 90/NR 20 (22) 0  
Lin et al [22]. Lap 3/4 5.3 (1.1) 1.9 ± 0.9 NR 3.3  ± 1.8 100/NR 3 (27) 0 0
Open 19/17 5.7 (1.9) 2.1 ±  1.0 NR 4.2  ± 2.2 100/NR 13 (36) 0  
Jung et al [21]. Lap 18/6 5.23 (2.13) NR 23/1 2.81 ± 1.72 100/96 NR 0 0
Open 16/8 5.56 (1.93) NR 18/6 3.23 ± 2.21 100/100 NR 0  
Hu et al [18]. Lap 8/5 NR NR NR 3.2 ± 1.0 NR/NR 0 (0) 0 0
Open 8/5 NR NR NR 3.5 ± 0.9 NR/NR 0 (0) 0  
Huh et al [19]. Lap 7/13 4 (2–10) 2 (1–7) 17/3 2 (0.9–5.5) 100/NR NR 0 0
Open 11/9 4.7 (3–7) 2 (1–8) 16/4 2.4 (1–10) 100/NR NR 0  
Chen et al [15]. Lap 0/23 2.5 (0.9) NR NR 5.5 ± 1.2 NR/NR NR 0 0
Open 0/18 2.3 (1.0) NR NR 5.6 ± 1.4 NR/NR NR 0  
  1. Lap Laparoscopic surgery, NR Not report
  2. aThe number of patients with CRLM ≥ 3