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Table 4 Disease-free survival analysis by clinicopathologic variables and body composition factors

From: Prognostic role of pre-sarcopenia and body composition with long-term outcomes in obstructive colorectal cancer: a retrospective cohort study

Variable

Analysis

Univariate

Multivariable

HR [95% CI]

P value

HR [95% CI]

P value

Sex, male

1.09 [0.63–1.88]

0.818

–

–

Age > 60

1.03 [0.60–1.78]

0.908

  

ASA (I vs II + III + IV)

1.08 [0.60–1.94]

0.790

–

–

Stage (II vs III)

6.27 [2.13–17.39]

< 0.001

3.64 [1.14–11.67]

0.030

Vascular invasion

2.05 [1.09–3.84]

0.026

1.77 [0.92–3.37]

0.087

Lymphatic invasion

3.81 [1.72–8.44]

0.001

1.76 [0.70–4.43]

0.229

Pre-operative CEA level > 5

2.17 [1.25–3.75]

0.006

2.226 [1.28–3.87]

0.005

Neutrophil lymphocyte ratio ≥ 5

0.31 [0.35–1.34]

0.702

  

Differentiation (well vs moderate +poor)

1.70 [0.41–7.01]

0.461

–

–

BMI ≥ 25

0.69 [0.36–1.35]

0.265

–

–

Visceral obesity ≥ 130[33]

0.65 [0.34–1.27]

0.206

–

–

Subcutaneous fat area (cm2) > 92a

0.80 [0.47–1.37]

0.417

–

–

Abdominal circumference (cm) > 83a

0.89 [0.52–1.52]

0.663

–

–

CONUT score > 7[22]

0.91 [0.22–3.79]

0.892

–

–

Pre-sarcopenia, men < 46.4 cm2, women < 37.5 cm2 [32]

1.83 [1.08–3.22]

0.023

1.86 [1.04-3.13]

0.037

  1. CI confidence interval, ASA American Society of Anesthesiologist physical status, CEA carcinoembryonic antigen, BMI body mass index, CONUT Controlling Nutritional Status
  2. aMedian value