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Table 3 Univariate and multivariate analyses of disease-free survival (DFS) related to clinical variables

From: Different surgical outcome and follow-up status between dMMR and pMMR colorectal cancer patients who fulfilled with Amsterdam-II criteria

Characteristics N DFS (%) p value Multiple Cox
1 year 3 years 5 years HR 95% C.I. p
HNHPCC      < 0.001    
 pMMR 51 84.00 67.94 63.40   1   
 dMMR 110 96.25 94.37 93.42   0.28 (0.108~0.733) 0.009
Sex      0.147    
 F 86 95.18 89.14 86.65     
 M 75 89.13 82.27 0.00     
Operation type      0.029    
 Hemicolectomy 111 88.75 80.24 78.27   1   
 Sub/total colectomy 50 100.00 98.00 96.00   0.41 (0.113~1.523) 0.185
Tumor location      < 0.001    
 Right colon 82 97.48 93.67 93.67   1   
 Left colon 48 89.58 85.42 81.14   1.93 (0.601~6.212) 0.269
 Rectum 31 82.76 65.52 62.07   1.97 (0.581~6.663) 0.276
Tumor histology      0.522    
 Adenocarcinoma 134 92.34 85.41 83.03     
 Mucinous/signet ring 23 95.45 90.91 90.91     
 Unclassified 4 75.00 75.00 75.00     
Tumor differentiation      0.360    
 Well 29 100.00 96.55 92.69     
 Moderate 100 89.75 82.52 80.41     
 Poor 29 92.86 85.71 85.71     
TNM_T stage      0.678    
 1 13 100.00 92.31 92.31   1   
 2 14 92.86 92.86 92.86   0.58 (0.052~6.567) 0.662
 3 82 91.22 83.61 79.67   0.75 (0.147~3.786) 0.724
 4 52 92.00 86.00 86.00   0.86 (0.154~4.773) 0.861
TNM_N stage      < 0.001    
 0 111 98.13 92.52 91.54   1   
 1 33 93.84 90.61 87.25   1.10 (0.314~3.873) 0.879
 2 16 50.00 37.50 31.25   11.22 (4.015~31.343) < 0.001
 3 1 100.00   125.71 (9.975~1584.441) < 0.001