Table 3 Meta-analysis for DFS/PFS
Comparison | Studies | HR (95%CI) | PA value | I2 | PH value | Model | |
|---|---|---|---|---|---|---|---|
Overall | 7 | 2.28 (1.52, 3.41) | < 0.001 | 81.3 | < 0.001 | R | |
Subgroup | |||||||
Country | Asian | 6 | 2.63 (1.65, 4.17) | < 0.001 | 77.7 | 0.000 | R |
Non-Asian | 1 | 1.26 (0.99, 1.61) | 0.062 | – | – | R | |
Sample size | < 200 | 3 | 1.74 (1.08, 2.80) | 0.022 | 61.2 | 0.076 | R |
> 200 | 4 | 2.74 (1.37, 5.46) | 0.004 | 88.6 | 0.000 | R | |
Cutoff | < 600 | 3 | 1.74 (1.08, 2.80) | 0.022 | 61.2 | 0.076 | R |
> 600 | 4 | 2.74 (1.37, 5.46) | 0.004 | 88.6 | 0.000 | R | |
Cancer type | |||||||
Cervical cancer | – | – | – | – | – | – | |
Ovarian cancer | 3 | 2.78 (1.04, 7.45) | 0.042 | 90.2 | 0.000 | R | |
Breast cancer | 4 | 2.05 (1.30, 3.24) | 0.002 | 72.3 | 0.013 | R | |
TNBC | 2 | 2.02 (1.05, 3.89) | 0.035 | 81.4 | 0.021 | R | |
Other BC type | 2 | 2.64 (0.67, 10.39) | 0.166 | 79.7 | 0.026 | R | |
Follow-up | |||||||
< 48 m | 4 | 2.42 (1.66, 3.52) | 0.010 | 88.0 | 0.000 | R | |
> 48 m | 3 | 1.98 (1.16, 3.37) | 0.005 | 70.8 | 0.033 | R | |