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Table 2 Univariate and multivariate survival analysis for risk factors for overall survival and disease-free survival

From: Loss of survival advantage for deficient mismatch repair in patients with advanced colorectal cancer may be caused by changes in prognostic value of CD8+T cell

  Univariate
for OS
Multivariate for OS Univariate
for DFS
Multivariate for DFS
Factors P HR (95% CI) P P HR (95% CI) P
CT-CD3(H/L) 0.005 0.026 (0.050–0.685) 0.012 0.006 0.217 (0.067–0.700) 0.011
IM-CD3(H/L) 0.091 0.242 (0.065–0.899) 0.034 0.027 0.188 (0.058–0.617) 0.006
CT-CD4(H/L) 0.069 0.261 0.192 0.222
IM-CD4(H/L) 0.002 0.029 (0.005–0.187) 0.001 0.011 0.077 (0.018–0.329) 0.001
CT-CD8(H/L) 0.114 0.320 0.083 0.274
IM-CD8(H/L) 0.770 0.847 0.795 0.452
IS(H/L) 0.005 0.121 0.007 0.098 (0.013–0.755) 0.026
CT-PD-L1 (+/−) 0.382 0.439 0.245 0.375
IM-PD-L1 (+/−) 0.688 0.711 0.233 0.497
  1. OS overall survival, DFS disease-free survival, HR hazard ratio, CT center of tumor, IM invasive margin, IS immunoscore