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Table 1 Clinical and pathological information for patients with dMMR and matched patients with pMMR

From: Loss of survival advantage for deficient mismatch repair in patients with advanced colorectal cancer may be caused by changes in prognostic value of CD8+T cell

Group

Stage I&II

dMMR (n = 32)

Stage III&IV

dMMR (n = 32)

P value

(I&II vs. III&IV)

Stage I-IV

pMMR (n = 64)

P value

(dMMR vs. pMMR)

Age(year)

62.66 ± 13.85

62.59 ± 17.35

0.987

62.84 ± 12.34

0.592

Sex, n (%)

  

0.614

 

1.000

 Male

17 (53.1%)

19 (59.4%)

 

36 (56.3%)

 

 Female

15 (46.9%)

13 (40.6%)

 

28 (43.8%)

 

BMI (kg/m2)

23.84 ± 3.92

22.87 ± 3.15

0.280

24.44 (21.78–25.68)

0.475

Tumor location

  

0.805

 

1.000

 Right-sided

19 (59.4%)

21 (65.6%)

 

40 (62.5%)

 

 Left-sided

6 (18.8%)

6 (18.8%)

 

12 (18.8%)

 

 Rectum

7 (21.9%)

5 (15.6%)

 

12 (18.8%)

 

UICC-TNM stage

  

/

 

1.000

 I

8 (25%)

  

8 (12.5%)

 

 II

24 (75%)

  

24 (37.5%)

 

 III

 

28 (87.5%)

 

28 (43.8%)

 

 IV

 

4 (12.5%)

 

4 (6.2%)

 

Tumor deposit

  

0.148

 

0.826

 Negative

30 (93.8%)

25 (78.1%)

 

54 (84.4%)

 

 Positive

2 (6.2%)

7 (21.1%)

 

10 (15.6%

 

PNI

  

0.277

 

0.219

 Negative

29 (90.6%)

26 (81.3%)

 

48 (75.0%)

 

 Positive

3 (9.4%)

6 (18.8%)

 

16 (25.0%)

 

Follow-up time

51.14 (28.80–79.43)

41.03 (19.24–61.76)

0.151

49.26 (28.73–69.20)

0.343

Length of hospital stay

18.38 (11.25–25.5)

19.09 (13–25.5)

0.770

16.22 (13–18)

0.550

Differentiation

  

0.486

 

0.046

 High

1 (3.1%)

0

 

2 (3.1%)

 

 Medium

19 (59.4%)

17 (53.1%)

 

48 (75.0%)

 

 Low

12 (37.5%)

15 (46.9%)

 

14 (21.9%)

 
  1. BMI body mass index, UICC Union for International Cancer Control, PNI perineural invasion