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Table 1 Clinical and pathological information for patients with dMMR and matched patients with pMMR

From: Loss of survival advantage for deficient mismatch repair in patients with advanced colorectal cancer may be caused by changes in prognostic value of CD8+T cell

Group Stage I&II
dMMR (n = 32)
Stage III&IV
dMMR (n = 32)
P value
(I&II vs. III&IV)
Stage I-IV
pMMR (n = 64)
P value
(dMMR vs. pMMR)
Age(year) 62.66 ± 13.85 62.59 ± 17.35 0.987 62.84 ± 12.34 0.592
Sex, n (%)    0.614   1.000
 Male 17 (53.1%) 19 (59.4%)   36 (56.3%)  
 Female 15 (46.9%) 13 (40.6%)   28 (43.8%)  
BMI (kg/m2) 23.84 ± 3.92 22.87 ± 3.15 0.280 24.44 (21.78–25.68) 0.475
Tumor location    0.805   1.000
 Right-sided 19 (59.4%) 21 (65.6%)   40 (62.5%)  
 Left-sided 6 (18.8%) 6 (18.8%)   12 (18.8%)  
 Rectum 7 (21.9%) 5 (15.6%)   12 (18.8%)  
UICC-TNM stage    /   1.000
 I 8 (25%)    8 (12.5%)  
 II 24 (75%)    24 (37.5%)  
 III   28 (87.5%)   28 (43.8%)  
 IV   4 (12.5%)   4 (6.2%)  
Tumor deposit    0.148   0.826
 Negative 30 (93.8%) 25 (78.1%)   54 (84.4%)  
 Positive 2 (6.2%) 7 (21.1%)   10 (15.6%  
PNI    0.277   0.219
 Negative 29 (90.6%) 26 (81.3%)   48 (75.0%)  
 Positive 3 (9.4%) 6 (18.8%)   16 (25.0%)  
Follow-up time 51.14 (28.80–79.43) 41.03 (19.24–61.76) 0.151 49.26 (28.73–69.20) 0.343
Length of hospital stay 18.38 (11.25–25.5) 19.09 (13–25.5) 0.770 16.22 (13–18) 0.550
Differentiation    0.486   0.046
 High 1 (3.1%) 0   2 (3.1%)  
 Medium 19 (59.4%) 17 (53.1%)   48 (75.0%)  
 Low 12 (37.5%) 15 (46.9%)   14 (21.9%)  
  1. BMI body mass index, UICC Union for International Cancer Control, PNI perineural invasion