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Table 1 The characteristics of included RCTs

From: Radiofrequency ablation versus laparoscopic hepatectomy for treatment of hepatocellular carcinoma: a systematic review and meta-analysis

Studies Group Participants Age(years) Gender (male/female) Child grade A/B Conclusions
Casaccia 2017 [17] RFA 22 60.82±7.25 16/6 20/2 The results confirm the superiority of Hepatic resection on thermoablation in the treatment of Small HCC in selected patients
LH 24 63.58±9.55 18/6 22/2
He 2016 [18] RFA 38 54.1±11.2 30/8 28/10 Radiofrequency ablation has more favorable clinical efficacy, less pain and better quality of life of patients than laparoscopic hepatectomy
LH 41 52.7±9.4 28/13 30/11
Lai 2016 [10] RFA 33 62.8±11.3 23/26 29/4 LH may provide better curative effects than pRFA without increasing complication rates.
LH 28 56.5±12.6 22/27 24/4
Song 2015 RFA 78 48 (43, 58) 70/8 76/2 There was no difference between LH and RFA in terms of OS in patients with a single, small HCC.
LH 78 48 (44,57) 70/8 78/0
Wang 2017 [20] RFA 65 66.47±16.13 36/29 47/18 Compared with LH, pRFA has higher success rate in the treatment of SCC.
LH 61 65.43±15.56 35/26 46/15
Xu 2017 [21] RFA 35 57.06±12.6 27/8 32/3 RFA and LH have similar efficacy for small primary liver cancer
LH 30 52.83±9.4 25/5 29/1
Yazici 2016 RFA 41 73.7±6.7 24/17 N/A LH was tolerated as well as RFA in elderly patients with similar comorbidities
LH 41 72.6±5.0 25/16 N/A
  1. Notes: HCC, hepatocellular carcinoma; LH, laparoscopic hepatectomy; pRFA, percutaneous radiofrequency ablation; OS, overall survival; N/A, not available