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Table 1 Summary of patients with GI metastasis from HCC in case report literature

From: Colon metastasis from hepatocellular carcinoma: a case report and literature review

Study (year)

Age

Sex

Underlying liver disease

Symptom

Site of metastasis

Interval (year)

Previous treatment

Survival period

Zhu et al. (2016) [8]

47

M

Hepatitis B

Positive in FOBT*

Transverse colon

5

Surgery, TAEâ—‡, TACEâ—†

Over 12 months

Yoo et al. (2010) [9]

47

M

Hepatitis B

Abdominal pain

Sigmoid colon

1.5

TACE

Over 4 months

Igawa et al. (2013) [10]

60

M

Liver cirrhosis type B

Melena and anemia

Ileum

Unknown

Chemotherapy

2 months

Huang et al. (2011) [11]

57

F

Hepatitis C

Bloody stool

Rectum

1.5

Surgery

Unknown

Nozaki et al. (2008) [12]

69

M

Unknown

Abdominal pain and hematochezia

Ascending colon

2

Surgery

Less than 1 month

Tapuria et al. (2007) [13]

67

M

Autoimmune chronic active hepatitis

Bleeding per rectum, anemia

Proximal ascending colon

10

Immunosuppression

A few months

Kohli et al. (2014) [14]

50

F

Cryptogenic cirrhosis

Hematochezia

Splenic flexure

4

Orthotopic liver transplant, radioembolization

Unknown

Ou et al. (2014) [15]

62

M

Hepatitis B

Tenesmus

Ascending colon and rectum

3

Surgery, RFA☆, PEI★, CyberKnife stereotactic radiosurgery, TACE

1 month

Kanazawa et al. (2018) [16]

76

M

Alcoholic cirrhosis

Lightheadedness and melena

Upper jejunum and 5 cm from the lesion on the anal side

Unknown

Surgery, TACE, sorafenib

2 weeks

Iwaki et al. (2008) [17]

60

M

Acute hepatitis, hepatitis C, liver cirrhosis

Asymptomatic

Jejunum

4

Surgery, RFA, TACE

Unknown

Yang et al. (1987) [18]

31

M

Unknown

Anemia

Proximal jejunum

1.5

Surgery

Unknown

Cosenza et al. (1999) [19]

82

F

Hepatitis C

Weakness, fatigue, bright red blood per rectum

Ascending colon

4

Surgery, chemotherapy

Unknown

Kim et al. (1999) [20]

65

M

Hepatitis B

Periumbilical pain

Jejunum

3

None

Unknown

Hirashita et al. (1999) [21]

79

M

Hepatitis C

Epigastralgia

Transverse colon

1.5

TACE

6 months

 

69

M

Hepatitis C

Melena and abdominal distension

Hepatic flexure and diaphragm

2.5

RFA and TACE

1 month

  1. *FOBT, fecal occult blood test
  2. â—‡TAE, transcatheter arterial embolization
  3. â—†TACE, transcatheter arterial angiography and chemoembolization
  4. ☆RFA, radiofrequency ablation
  5. ★,PEI, percutaneous ethanol injection