Clinicopathological and prognostic significance of platelet-lymphocyte ratio (PLR) in gastric cancer: an updated meta-analysis

Table 3 Meta-analysis of the association between PLR and clinicopathological parameters of GC

Variable	No. of studies	No. of patients	Effects model	OR (95% CI)	p	Heterogeneity
Variable	No. of studies	No. of patients	Effects model	OR (95% CI)	p	I²	P_h
Tumor differentiation (moderate/high vs. poor)	18	6721	Fixed	1.04 (0.98–1.11)	0.173	7.30%	0.367
Tumor location (cardia vs. non-cardia)	10	2905	Fixed	0.99 (0.87–1.12)	0.837	6.00%	0.386
Tumor size (≤ 5 vs. > 5 cm)	8	2596	Random	1.04 (0.88–1.23)	0.634	74.20%	< 0.001
Lymph node metastasis (no vs. yes)	15	6752	Random	1.17 (1.02–1.33)	0.023	71.90%	< 0.001
Depth of invasion (T1–T2 vs. T3–T4 )	13	6250	Random	1.34 (1.10–1.64)	0.003	86.20%	< 0.001
TNM (Tis-II vs. III-IV)	16	6834	Random	1.20 (1.06–1.37)	0.004	77.30%	< 0.001

OR odds ratio, 95% CI 95% confidence interval, P_hp values of Q test for heterogeneity test