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Table 3 Meta-analysis of the association between PLR and clinicopathological parameters of GC

From: Clinicopathological and prognostic significance of platelet-lymphocyte ratio (PLR) in gastric cancer: an updated meta-analysis

Variable No. of studies No. of patients Effects model OR (95% CI) p Heterogeneity
I2 Ph
Tumor differentiation (moderate/high vs. poor) 18 6721 Fixed 1.04 (0.98–1.11) 0.173 7.30% 0.367
Tumor location (cardia vs. non-cardia) 10 2905 Fixed 0.99 (0.87–1.12) 0.837 6.00% 0.386
Tumor size (≤ 5 vs. > 5 cm) 8 2596 Random 1.04 (0.88–1.23) 0.634 74.20% < 0.001
Lymph node metastasis (no vs. yes) 15 6752 Random 1.17 (1.02–1.33) 0.023 71.90% < 0.001
Depth of invasion (T1–T2 vs. T3–T4 ) 13 6250 Random 1.34 (1.10–1.64) 0.003 86.20% < 0.001
TNM (Tis-II vs. III-IV) 16 6834 Random 1.20 (1.06–1.37) 0.004 77.30% < 0.001
  1. OR odds ratio, 95% CI 95% confidence interval, Php values of Q test for heterogeneity test