From: Comparison of non-schistosomal colorectal cancer and schistosomal colorectal cancer
Characteristics | All patients (N = 351) | Patients with stage I–II disease (N = 192) | Patients with stage III–IV disease (N = 159) | Patients with LNM (N = 144) | Patients without LNM (N = 207) | |||||
---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | |
Age (< 60 years) | 83 | 24 | 46 | 24 | 37 | 23 | 34 | 24 | 49 | 23 |
Gender (male) | 214 | 61 | 118 | 61 | 65 | 59 | 71 | 49 | 123 | 57 |
Tumor location | ||||||||||
Rectum | 94 | 27 | 50 | 26 | 44 | 28 | 37 | 26 | 57 | 28 |
Left colon | 115 | 33 | 61 | 32 | 54 | 34 | 51 | 35 | 64 | 31 |
Right colon | 142 | 40 | 81 | 42 | 61 | 38 | 56 | 39 | 86 | 41 |
Tumor size (< 5 cm) | 174 | 50 | 94 | 50 | 80 | 49.7 | 71 | 49 | 103 | 48 |
Differentiation | ||||||||||
Well diff. | 267 | 76 | 165 | 86 | 102 | 65 | 93 | 65 | 173 | 82 |
Poor diff. | 84 | 24 | 27 | 14 | 57 | 35 | 51 | 35 | 36 | 18 |
Lymphovascular invasion (positive) | 122 | 35 | 46 | 24 | 76 | 48 | 68 | 47 | 54 | 26 |
Nervous invasion (positive) | 31 | 1.0 | 12 | 6.0 | 19 | 12 | 18 | 12.5 | 13 | 6 |
Lymph nodes positive for CRC (> 2) | 42 | 1.2 | 1.0 | 0.0 | 41 | 26 | 35 | 24 | 7 | 3 |
Colonic perforation (yes) | 13 | 0.4 | 8 | 4.0 | 5 | 3.0 | 4 | 3.0 | 9 | 4.0 |
Tumor budding (≥ 5 cells) | 219 | 62 | 99 | 52 | 120 | 75 | 110 | 79 | 109 | 53 |
Ulceration (yes) | 149 | 42 | 79 | 41 | 70 | 44 | 64 | 44 | 85 | 41 |
Histological type | ||||||||||
Adenocarcinoma | 311 | 89 | 173 | 90 | 138 | 87 | 124 | 86 | 187 | 90 |
Mucinous/SRCC | 40 | 11 | 19 | 10 | 21 | 13 | 20 | 14 | 20 | 10 |
Pathological T stage | ||||||||||
T1–2 | 80 | 23 | 65 | 34 | 15 | 9 | 14 | 10 | 63 | 31 |
T3–4 | 271 | 77 | 127 | 66 | 144 | 91 | 130 | 90 | 146 | 69 |
Lymph node metastasis | ||||||||||
No | 207 | 60 | 189 | 98 | 18 | 12 | – | – | – | – |
Yes | 144 | 40 | 3 | 2 | 141 | 88 | – | – | – | – |
TNM stage | ||||||||||
I + II | 190 | 54 | – | – | – | – | 3 | 2 | 192 | 92 |
III + IV | 161 | 46 | – | – | – | – | 141 | 98 | 17 | 8 |
Schistosomiasis | 137 | 39 | 76 | 40 | 61 | 38 | 56 | 39 | 81 | 40 |