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Table 2 Characteristics and preoperative data of patients undergoing major hepatectomy

From: Splenic enlargement induced by preoperative chemotherapy is a useful indicator for predicting liver regeneration after resection for colorectal liver metastases

CharacteristicsChemotherapyNo chemotherapy (n = 30)p value
SP index ≥ 1.2 (n = 12)SP index < 1.2 (n = 14)
Gender (male/female)8/48/614/160.48
Age58.3 ± 12.463.6 ± 10.363.0 ± 10.00.38
BMI22.9 ± 3.121.3 ± 2.722.8 ± 3.80.23
Diabetes mellitus (+)4350.49
Hepatitis virus (+)0020.41
Number of chemotherapy cycles (median, range)12 (5–27)8 (1–23)0.21
SP index1.65 ± 0.601.04 ± 0.05< 0.001
Splenic volume before chemotherapy131.7 ± 48.2112.4 ± 49.40.23
Splenic volume before hepatectomy214.3 ± 88.8117.7 ± 56.9160.9 ± 162.00.004
Laboratory tests before hepatectomy
 Platelet count (× 109/L)171 ± 60231 ± 97234 ± 720.029
 AST (IU/L)33.3 ± 11.724.8 ± 7.826.7 ± 9.30.035
 ALT (IU/L)30.5 ± 18.919.2 ± 13.622.2 ± 13.50.032
 ALP (IU/L)371.6 ± 161.3410.9 ± 186.3303.8 ± 159.20.050
 Albumin (g/dL)3.9 ± 0.33.9 ± 0.44.1 ± 0.20.014
T-Bil (mg/dL)0.9 ± 0.40.9 ± 0.40.9 ± 0.30.94
 PT-INR1.02 ± 0.081.04 ± 0.091.08 ± 0.100.17
 ICG-R15 (%)12.3 ± 5.910.2 ± 6.07.9 ± 3.90.061
Future remnant liver volume (%)55.9 ± 12.849.3 ± 18.553.5 ± 13.80.42
TSH/PVE3420.12
  1. Continuous data are presented as mean ± standard deviation
  2. BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, T-Bil total bilirubin, PT-INR prothrombin time international normalized ratio, ICG-R15 indocyanine green retention rate at 15 min, TSH two stage hepatectomy, PVE portal vein embolization