Fig 1

Changes in splenic volume during chemotherapy. a Splenic volume before and after preoperative chemotherapy (n = 51). b The relationship between SP index and chemotherapeutic regimen. IRI-based: FOLFIRI/IRIS with or without biologics (n = 20). OX-based: FOLFOX/CapeOX with or without anti-EGFR monoclonal antibodies (n = 18). OX + Bmab: FOLFOX/CapeOX with bevacizumab (n = 11). c SP index in patients who had 9 or more cycles of chemotherapy. d SP index in patients who had 8 or fewer cycles of chemotherapy. Data are mean ± standard error of the mean. A comparison was performed using the Mann-Whitney U test. A p value < 0.05 was considered to be significant