Table 3 Univariate and multivariable Cox regression analyses for RFS
From: Patterns of recurrence in adenocarcinoma of the esophagogastric junction: a retrospective study
Factor | Recurrence incidence (%) | Univariable | Multivariable | |||
|---|---|---|---|---|---|---|
S | S+CT | HR (95% CI) | P value | HR (95% CI) | P value | |
Age, years (≦ 63/> 63) | 80.7/91.5 | 74.1/81.6 | 1.451 (1.130–1.863) | 0.03 | 1.282 (0.996–1.651) | 0.054 |
Sex (male/female) | 87.2/84.6 | 77.5/74.0 | 0.890 (0.610–1.298) | 0.546 | NA | |
Histology (AC/mucinous AC) | 85.7/92.0 | 76.0/80.0 | 1.072 (0.800–1.436) | 0.642 | NA | |
Tumor length, cm (≦ 5.5/> 5.5) | 88.5/84.9 | 76.8/77.2 | 0.979 (0.762–1.257) | 0.865 | NA | |
pT stage (T2, T3/T4a) | 92.9/73.6 | 78.5/75.0 | 0.804 (0.618–1.045) | 0.103 | NA | |
pN stage (N0, N1, N2/N3) | 82.4/93.8 | 64.3/98.5 | 2.624 (2.021–3.407) | < 0.001 | 2.533 (1.951–3.289) | < 0.001 |
pTNM stage (IIIa, IIIb/IIIc) | 84.3/89.8 | 61.1/90.8 | 2.087 (1.614–2.698) | < 0.001 | 1.214 (0.804–1.833) | 0.356 |
ALI (no/yes) | 87.5/85.7 | 72.5/85.7 | 1.222 (0.938–1.592) | 0.138 | NA | |
PNI (no/yes) | 88.7/84.6 | 74.7/80.0 | 1.266 (0.984–1.627) | 0.067 | NA | |
Method of resection (TTE/TAE) | 88.5/84.9 | 88.2/66.1 | 0.799 (0.614–1.040) | 0.096 | NA | |
Treatment arm (S/S+CT) | 86.9 | 77.0 | 0.637 (0.495–0.820) | < 0.001 | 0.668 (0.519–0.861) | 0.02 |
Number of resected lymph nodes (≦ 19/> 19) | 87.1/77.0 | 86.8/77.1 | 0.954 (0.743–1.224) | 0.712 | NA | |