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Table 3 Univariate and multivariable Cox regression analyses for RFS

From: Patterns of recurrence in adenocarcinoma of the esophagogastric junction: a retrospective study

Factor Recurrence incidence (%) Univariable Multivariable
S S+CT HR (95% CI) P value HR (95% CI) P value
Age, years ( 63/> 63) 80.7/91.5 74.1/81.6 1.451 (1.130–1.863) 0.03 1.282 (0.996–1.651) 0.054
Sex (male/female) 87.2/84.6 77.5/74.0 0.890 (0.610–1.298) 0.546 NA  
Histology (AC/mucinous AC) 85.7/92.0 76.0/80.0 1.072 (0.800–1.436) 0.642 NA  
Tumor length, cm ( 5.5/> 5.5) 88.5/84.9 76.8/77.2 0.979 (0.762–1.257) 0.865 NA  
pT stage (T2, T3/T4a) 92.9/73.6 78.5/75.0 0.804 (0.618–1.045) 0.103 NA  
pN stage (N0, N1, N2/N3) 82.4/93.8 64.3/98.5 2.624 (2.021–3.407) < 0.001 2.533 (1.951–3.289) < 0.001
pTNM stage (IIIa, IIIb/IIIc) 84.3/89.8 61.1/90.8 2.087 (1.614–2.698) < 0.001 1.214 (0.804–1.833) 0.356
ALI (no/yes) 87.5/85.7 72.5/85.7 1.222 (0.938–1.592) 0.138 NA  
PNI (no/yes) 88.7/84.6 74.7/80.0 1.266 (0.984–1.627) 0.067 NA  
Method of resection (TTE/TAE) 88.5/84.9 88.2/66.1 0.799 (0.614–1.040) 0.096 NA  
Treatment arm (S/S+CT) 86.9 77.0 0.637 (0.495–0.820) < 0.001 0.668 (0.519–0.861) 0.02
Number of resected lymph nodes ( 19/> 19) 87.1/77.0 86.8/77.1 0.954 (0.743–1.224) 0.712 NA