| Epidemiology | | | | |
| Sex, male | 0.64 | | 0.29 | |
| HBs-Ag positive | 0.24 | | 0.09 | |
| HCV-Ab positive | 0.28 | | 0.94 | |
| NBNC | 0.07 | | 0.63 | |
| Biochemical factors | | | | |
| Platelets < 100,000/mm3 | 0.50 | | 0.42 | |
| PA < 80% | < 0.01 | 0.02 (8.109) (1.227–53.587) | 0.57 | |
| ChE < 180 IU/l | 0.01 | 0.35 (2.021) (0.447–9.127) | 0.70 | |
| Albumin < 3.5 g/dl | 0.24 | | 0.43 | |
| ICGR15 ≥ 15% | 0.06 | | 0.77 | |
| AFP ≥ 20 ng/ml | 0.11 | | < 0.01 | 0.85 (0.911) (0.339–2.444) |
| PIVKA-II ≥ 400 mAU/ml | < 0.01 | 0.03 (9.838) (1.220–79.309) | 0.01 | 0.02 (4.038) (1.147–14.211) |
| Tumor factors | | | | |
| Tumor size ≥ 10 cm | 0.03 | 0.65 (0.707) (0.157–3.189) | < 0.01 | 0.27 (0.424) (0.089–2.006) |
| Tumor number multiple | 0.93 | | 0.04 | 0.20 (2.115) (0.672–6.657) |
| Macroscopic type except simple nodular | 0.42 | | 0.03 | 0.05 (2.646) (0.982–7.127) |
| Histological factors | | | | |
| Differentiation, poor | 0.35 | | 0.02 | 0.45 (1.440) (0.552–3.757) |
| PVI | 0.75 | | 0.01 | 0.01 (4.580) (1.342–15.629) |
| HVI | 0.24 | | 0.02 | < 0.01 (7.393) (1.923–28.424) |
| Fibrosis | 0.57 | | 0.02 | 0.01 (3.483) (1.258–9.644) |
| Surgical factors | | | | |
| FRLR < 50% | 0.03 | 0.81 (1.204) (0.245–5.911) | 0.17 | |
| Non-anatomical resection | 0.80 | | 0.99 | |
| Blood loss ≥ 400 ml | < 0.01 | 0.18 (5.000) (0.470–53.111) | 0.77 | |
