Table 4 Prognostic factors for survival and recurrence of very elderly patients

Epidemiology

 Sex, male

0.64

0.29

 HBs-Ag positive

0.24

0.09

 HCV-Ab positive

0.28

0.94

 NBNC

0.07

0.63

Biochemical factors

 Platelets < 100,000/mm³

0.50

0.42

 PA < 80%

< 0.01

0.02 (8.109) (1.227–53.587)

0.57

 ChE < 180 IU/l

0.01

0.35 (2.021) (0.447–9.127)

0.70

 Albumin < 3.5 g/dl

0.24

0.43

 ICGR15 ≥ 15%

0.06

0.77

 AFP ≥ 20 ng/ml

0.11

< 0.01

0.85 (0.911) (0.339–2.444)

 PIVKA-II ≥ 400 mAU/ml

< 0.01

0.03 (9.838) (1.220–79.309)

0.01

0.02 (4.038) (1.147–14.211)

Tumor factors

 Tumor size ≥ 10 cm

0.03

0.65 (0.707) (0.157–3.189)

< 0.01

0.27 (0.424) (0.089–2.006)

 Tumor number multiple

0.93

0.04

0.20 (2.115) (0.672–6.657)

 Macroscopic type except simple nodular

0.42

0.03

0.05 (2.646) (0.982–7.127)

Histological factors

 Differentiation, poor

0.35

0.02

0.45 (1.440) (0.552–3.757)

 PVI

0.75

0.01

0.01 (4.580) (1.342–15.629)

 HVI

0.24

0.02

< 0.01 (7.393) (1.923–28.424)

 Fibrosis

0.57

0.02

0.01 (3.483) (1.258–9.644)

Surgical factors

 FRLR < 50%

0.03

0.81 (1.204) (0.245–5.911)

0.17

 Non-anatomical resection

0.80

0.99

 Blood loss ≥ 400 ml

< 0.01

0.18 (5.000) (0.470–53.111)

0.77