|
Characteristics
|
n
|
6-year disease-free survival
|
P
|
6-year overall survival
|
P
|
|---|
|
OATP1B3
| | |
0.000
| |
0.001
|
|
Low expression
|
78
|
5.3%
| |
12.9%
| |
|
High expression
|
53
|
18.8%
| |
33.0%
| |
|
Age (year)
| | |
0.933
| |
0.590
|
|
≥ 50
|
56
|
9.4%
| |
23.2%
| |
|
< 50
|
75
|
11.2%
| |
19.8%
| |
|
Sex
| | |
0.418
| |
0.735
|
|
Male
|
104
|
10.6%
| |
20.0%
| |
|
Female
|
27
|
11.1%
| |
25.9%
| |
|
Tumor size
| | |
0.065
| |
0.205
|
|
≥ 5 cm
|
88
|
7.8%
| |
17.8%
| |
|
< 5 cm
|
43
|
15.0%
| |
28.9%
| |
|
TNM stage
| | |
0.000
| |
0.000
|
|
I, II
|
50
|
21.3%
| |
32.9%
| |
|
III, IV
|
81
|
3.5%
| |
13.8%
| |
|
Tumor differentiation
| | |
0.452
| |
0.076
|
|
Well
|
9
|
13.0%
| |
50.0%
| |
|
Moderate
|
101
|
10.5%
| |
15.6%
| |
|
Poor
|
21
|
10.6%
| |
36.1%
| |
|
Serum AFP
| | |
0.045
| |
0.037
|
|
≥ 20 ng/mL
|
89
|
7.3%
| |
18.0%
| |
|
< 20 ng/mL
|
42
|
16.1%
| |
28.0%
| |
|
Invasion
| | |
0.016
| |
0.026
|
|
Yes
|
58
|
6.8%
| |
14.8%
| |
|
No
|
73
|
13.5%
| |
26.5%
| |
|
HBsAg
| | |
0.386
| |
0.434
|
|
Positive
|
106
|
9.2%
| |
20.5%
| |
|
Negative
|
25
|
17.1%
| |
25.4%
| |
|
Tumor number
| | |
0.147
| |
0.371
|
|
Single
|
87
|
12.2%
| |
23.7%
| |
|
Multiple
|
44
|
7.1%
| |
16.0%
| |
|
Liver cirrhosis
| | |
0.682
| |
0.972
|
|
Yes
|
91
|
10.8%
| |
21.7%
| |
|
No
|
40
|
10.5%
| |
20.8%
| |
|
Tumor capsule
| | |
0.513
| |
0.785
|
|
Yes
|
45
|
11.1%
| |
23.6%
| |
|
No
|
86
|
0.99%
| |
20.2%
| |
- OATP1B3 organic anion transporting polypeptide 1B3, TNM stage tumor node metastasis stage, AFP alpha fetoprotein
