Skip to main content

Table 2 Overall survival and disease-free survival of 131 HCC patients by univariate analysis

From: Low expression of organic anion-transporting polypeptide 1B3 predicts a poor prognosis in hepatocellular carcinoma

Characteristics

n

6-year disease-free survival

P

6-year overall survival

P

OATP1B3

  

0.000

 

0.001

Low expression

78

5.3%

 

12.9%

 

High expression

53

18.8%

 

33.0%

 

Age (year)

  

0.933

 

0.590

 ≥ 50

56

9.4%

 

23.2%

 

 < 50

75

11.2%

 

19.8%

 

Sex

  

0.418

 

0.735

 Male

104

10.6%

 

20.0%

 

 Female

27

11.1%

 

25.9%

 

Tumor size

  

0.065

 

0.205

 ≥ 5 cm

88

7.8%

 

17.8%

 

 < 5 cm

43

15.0%

 

28.9%

 

TNM stage

  

0.000

 

0.000

 I, II

50

21.3%

 

32.9%

 

 III, IV

81

3.5%

 

13.8%

 

Tumor differentiation

  

0.452

 

0.076

 Well

9

13.0%

 

50.0%

 

 Moderate

101

10.5%

 

15.6%

 

 Poor

21

10.6%

 

36.1%

 

Serum AFP

  

0.045

 

0.037

 ≥ 20 ng/mL

89

7.3%

 

18.0%

 

 < 20 ng/mL

42

16.1%

 

28.0%

 

Invasion

  

0.016

 

0.026

 Yes

58

6.8%

 

14.8%

 

 No

73

13.5%

 

26.5%

 

HBsAg

  

0.386

 

0.434

 Positive

106

9.2%

 

20.5%

 

 Negative

25

17.1%

 

25.4%

 

Tumor number

  

0.147

 

0.371

 Single

87

12.2%

 

23.7%

 

 Multiple

44

7.1%

 

16.0%

 

Liver cirrhosis

  

0.682

 

0.972

 Yes

91

10.8%

 

21.7%

 

 No

40

10.5%

 

20.8%

 

Tumor capsule

  

0.513

 

0.785

 Yes

45

11.1%

 

23.6%

 

 No

86

0.99%

 

20.2%

 
  1. OATP1B3 organic anion transporting polypeptide 1B3, TNM stage tumor node metastasis stage, AFP alpha fetoprotein