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Table 1 Association between OATP1B3 expression and clinicopathological features of HCC patients

From: Low expression of organic anion-transporting polypeptide 1B3 predicts a poor prognosis in hepatocellular carcinoma

Characteristics   n OATP1B3 Low OATP1B3 High χ2 P
HCC   131 78 53 24.236 < 0.0001
Nontumor liver   89 23 66   
Age (year) ≥ 50 56 33 23 0.015 0.902
< 50 75 45 30   
Sex Male 104 61 43 0.165 0.684
Female 27 17 10   
Tumor size (cm) ≥ 5 88 59 29 6.266 0.012
< 5 43 19 24   
TNM stage I, II 50 19 31 15.578 < 0.0001
III, IV 81 59 22   
Tumor differentiation Well 9 0 9 17.716 < 0.0001
Moderate 101 61 40   
Poor 21 17 4   
Serum AFP ≥ 20 ng/mL 89 55 34 0.586 0.444
< 20 ng/mL 42 23 19   
Recurrence Yes 81 56 25 8.109 0.004
No 50 22 28   
HBsAg Positive 106 61 45 0.918 0.338
Negative 25 17 8   
Tumor number Single 87 47 40 3.275 0.07
Multiple 44 31 13   
Liver cirrhosis Yes 91 53 38 0.209 0.647
No 40 25 15   
Invasion Yes 58 36 22 0.276 0.599
No 73 42 31   
Tumor capsule Yes 45 27 18 0.006 0.938
No 86 51 35   
  1. AFP alpha fetoprotein, OATP1B3 organic anion transporting polypeptide 1B3, TNM stage tumor node metastasis stage, HCC hepatocellular carcinoma