Table 2 Univariable and multivariable Cox regression analyses predicting local recurrence in 389 patients who underwent a radical nephroureterectomy for upper tract urothelial carcinoma

Age > 70 years

1.125

0.771-1.78

0.615

 Male

1.121

0.708-1.775

0.626

 Female

1

 Left

1.213

0.766-1.92

0.409

 Right

1

 Pelvic

0.625

0.394-0.993

0.047

0.703

0.427-1.155

0.164

 Ureter

1

Focality

 Multifocality

2.005

1.226-3.446

0.006

2.116

1.246-3.593

0.006

 Unifocality

1

 TCC with other differentiation

0.921

0.546-1.555

0.759

 Complete TCC

1

 T3–4

4.153

2.554-6.78

0.000

2.805

1.588-4.957

0.000

 T1–2

1

 G3

4.674

2.744-7.963

0.000

2.991

1.659-5.393

0.000

 G1–2

1

LND

 Yes

2.802

1.727-4.548

0.000

1.129

0.547-2.334

0.742

 No

1

 Laparoscopic nephroureterectomy

0.678

0.389-1.181

0.678

 Open nephroureterectomy

1

 Yes

5.017

2.872-2.163

0.000

1.925

1.053-3.521

0.033

 No

1

LVI

 Yes

2.12

1.245-3.612

0.006

1.202

0.671-2.151

0.536

 No

1

 Yes

1.602

0.843-3.042

0.150

 No

1

 Yes

2.053

0.749-5.63

0.162

 No

1

 Yes

0.313

0.114-0.861

0.024

0.177

0.064-0.493

0.001

 No

1