Table 1 Patient clinical and pathological characteristic
Characteristics | All patients (%) | Patients with local recurrence (%) | Patients without local recurrence (%) | P value |
|---|---|---|---|---|
Patient number | 389 | 73 (18.8) | 316 (81.2) | Â |
Median age (range) | 69 (35-88) | 70 (37-85) | 69 (35-88) | Â |
Age group | Â | Â | Â | 0.620 |
 < 70 | 202 (51.9) | 36 (49.3) | 166 (52.5) |  |
 ≥ 70 | 187 (48.1) | 37 (50.7) | 150 (47.5) |  |
Gender | Â | Â | Â | 0.727 |
 Male | 190 (48.8) | 37 (50.7) | 153 (48.4) |  |
 Female | 199 (51.2) | 36 (49.3) | 163 (51.6) |  |
Site | Â | Â | Â | 0.393 |
 Left | 185 (47.6) | 38 (52.1) | 147 (46.5) |  |
 Right | 204 (52.4) | 35 (47.9) | 169 (53.5) |  |
Location | Â | Â | Â | 0.042 |
 Pelvic | 212 (54.5) | 32 (43.8) | 180 (57.0) |  |
 Ureter | 177 (45.5) | 41 (56.2) | 136 (43.0) |  |
Concomitant bladder tumor | Â | Â | Â | 0.192 |
 Yes | 42 (10.8) | 11 (15.1) | 31 (9.8) |  |
 No | 347 (89.2) | 62 (84.9) | 285 (90.2) |  |
Tumor type | Â | Â | Â | 0.599 |
 Complete TCC | 278 (71.5) | 54 (74.0) | 224 (70.9) |  |
 TCC with other differentiation | 111 (28.5) | 19 (26.0) | 92 (29.1) |  |
Surgical procedure | Â | Â | Â | 0.088 |
 Laparoscopic nephroureterectomy | 326 (83.8) | 57 (78.1) | 269 (85.1) |  |
 Open nephroureterectomy | 63 (16.2) | 16 (21.9) | 47 (14.9) |  |
Lymph vascular invasion | Â | Â | Â | 0.009 |
 Yes | 58 (14.9) | 18 (24.7) | 40 (12.7) |  |
 No | 331 (85.1) | 55 (75.3) | 276 (87.3) |  |
Tumor grade | Â | Â | Â | 0.000 |
 G1 | 6 (1.6) | 0 | 6 (1.9) |  |
 G2 | 209 (54.4) | 17 (23.6) | 192 (61.5) |  |
 G3 | 169 (44.0) | 55 (76.4) | 114 (36.5) |  |
Pathological stage | Â | Â | Â | 0.000 |
 T1 | 125 (32.6) | 9 (12.3) | 116 (36.7) |  |
 T2 | 121 (31.5) | 15 (20.5) | 105 (33.3) |  |
 T3 | 129 (33.6) | 48 (65.8) | 87 (27.5) |  |
 T4 | 9 (2.3) | 1 (1.4) | 8 (2.5) |  |
Lymph node detection | Â | Â | Â | 0.000 |
 No | 316 (81.2) | 48 (65.8) | 268 (84.8) |  |
 Yes | 73 (18.8) | 25 (34.2) | 48 (15.2) |  |
Lymph node involvement | Â | Â | Â | 0.000 |
 Nx | 316 (81.2) | 48 (65.8) | 268 (84.8) |  |
 N0 | 43 (11.1) | 9 (12.3) | 34 (10.8) |  |
 N1 | 11 (2.8) | 4 (5.5) | 7 (2.2) |  |
 N2 | 19 (4.9) | 12 (16.4) | 7 (2.2) |  |
Multifocality | Â | Â | Â | 0.013 |
 No | 321 (82.5) | 53 (72.6) | 268 (84.8) |  |
 Yes | 68 (17.5) | 20 (27.4) | 48 (15.2) |  |
Margin | Â | Â | Â | 0.189 |
 Positive margin | 12 (3.1) | 4 (5.5) | 8 (2.5) |  |
 Negative margin | 377 (96.9) | 69 (94.5) | 308 (97.5) |  |
Adjuvant radiotherapy | Â | Â | Â | 0.014 |
 Yes | 57 (14.7) | 4 (5.5) | 53 (16.8) |  |
 No | 332 (85.3) | 69 (94.5) | 263 (83.2) |  |