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Table 1 Comparison according to the type of hysterectomy in patients with endometrial carcinoma with cervical involvement (N = 239)

From: What is the impact of radical hysterectomy on endometrial cancer with cervical involvement?

 

SH, 200 (83.68%)

RH, 39 (16.32%)

Total, 239

p

Age, years¥

55.42 (46.9–63.9)

56.55 (48.7–62.4)

55.64 (47.2–63.5)

0.756

Weight, kg¥

67 (59.8–79.9)

66 (57–79)

7 (59–79.8)

0.643

BMI¥

28.55 (25.2–33.8)

27.83 (24.4–32.5)

28.51 (25.1–33.3)

0.600

Positive cytology§

82 (41)

21 (53.85)

103 (43.10)

0.138

Histology§

    

Endometrioid

154 (77)

23 (58.97)

177 (74.06)

0.007

Serous papillary

15 (7.5)

6 (16.38)

21 (8.79)

 

Clear cell

4 (2.0)

1 (2.56)

5 (2.09)

 

Mixed

26 (13.0)

6 (15.38)

32 (13.39)

 

Carcinosarcoma

1 (0.5)

3 (7.69)

4 (1.67)

 

Tumor size, mm¥

15 (5.3–70.0)

5 (6–50)

12 (5.5–65.0)

0.349

Grade§

    

 G1

9 (4.59)

4 (10.26)

13 (5.44)

0.130

 G2

96 (48.0)

14 (35.90)

110 (46.03)

 

 G3

39 (19.50)

5 (12.82)

44 (18.41)

 

 Poor prognostic histology

56 (28)

16 (41.03)

72 (30.13)

 

Lymphovascular invasion§

134 (72.43)

31 (83.78)

165 (74.32)

0.183

Myometrial involvement§

    

 Superficial

5 (2.50)

1 (2.56)

6 (2.51)

0.994

 < 50%

52 (26.00)

10 (25.64)

62 (25.94)

 

 > 50%

125 (62.50)

25 (64.10)

150 (62.76)

 

 NA

18 (9.0)

3 (7.69)

21 (8.79)

 

Depth of invasion, mm¥

5 (3–12)

10.5 (5–15)

6 (3–12.5)

0.005

Depth invasion/thickness rate¥

0.48 (0.25–0.67)

0.52 (0.4–0.87)

0.5 (0.25–0.92)

0.028

Ovarian involvement§

35 (17.50)

7 (17.95)

42 (17.57)

0.946

Parametrial involvement§

9 (4.50)

7 (17.95)

16 (6.69)

0.002

Uterine serosa involvement§

18 (9.0)

5 (12.82)

23 (9.62)

0.459

Pelvic lymph node involvement, n = 165§

55 (41.04)

15 (48.39)

70 (42.42)

0.456

Para-aortic lymph node involvement, n = 135§

34 (31.78)

6 (21.43)

40 (29.63)

0.286

Stage§

    

 II

87 (43.50)

11 (28.21)

98 (41.00)

0.124

 III

73 (36.50)

22 (56.41)

95 (39.75)

 

 IV

31 (15.5)

4 (10.26)

35 (14.64)

 

 NA

9 (4.50)

2 (5.13)

11 (4.60)

 

Any radiotherapy§±

150 (75.00)

32 (82.05)

182 (76.2)

0.345

Brachytherapy

135 (67.50)

30 (76.92)

165 (69.04)

0.244

External beam radiotherapy

124 (62)

29 (74.36)

153 (64.02)

0.141

Chemotherapy§

107 (53.50)

22 (56.41)

129 (53.97)

0.739

Recurrence§

46 (23.00)

11 (28.21)

57 (23.85)

0.485

Death§

35 (17.50)

5 (12.82)

40 (16.74)

0.474

  1. SH simple hysterectomy, RH radical hysterectomy, BMI body mass index, NA not applicable/unavailable
  2. ¥Median (interquartile range), statistical analysis: sum of ranks
  3. §Absolute value (relative analysis), statistical analysis: chi-squared
  4. ±Low-dose-rate brachytherapy, high-dose-rate brachytherapy, and external beam radiotherapy