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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: XIST promotes cell proliferation and invasion by regulating miR-140-5p and SOX4 in retinoblastoma

Fig. 4

miR-140-5p directly targets SOX4 in Y79 cells. a Putative target sites between miR-140-5p and SOX4. b Luciferase reporter assay demonstrated that miR-140-5p directly targeted SOX4. c miR-140-5p inhibited SOX4 expression levels in Y79 cells. d SOX4 mRNA expression was enhanced in RB tissues. e The correlation between miR-140-5p and SOX4 in RB tissues. f The correlation between XIST and SOX4 in RB tissues. *P < 0.05, **P < 0.01, and ***P < 0.001, compared with the miR-NC, NC, or normal group

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