Table 2 Results of a univariate analysis of the overall survival according to the clinicopathological factors
From: Outcomes of surgical resection for gastric cancer liver metastases: a retrospective analysis
Characteristics | n | HR | 95 % CI | p value* | |
|---|---|---|---|---|---|
Sex | Male | 13 | 0.64 | 0.19–2.24 | 0.459 |
Female | 7 | 1 | |||
Age (years) | > 70 | 13 | 0.20 | 0.05–0.67 | 0.004 |
< 70 | 7 | 1 | |||
Histological type | Well/mod | 14 | 2.10 | 0.54–13.77 | 0.331 |
Poor/muc | 6 | 1 | |||
Size of primary tumor (cm) | ≥ 5 | 10 | 4.10 | 1.02–20.4 | 0.041 |
< 5 | 10 | 1 | |||
Type of gastrectomy (partial; distal 11, proximal 1) | Total gastrectomy | 8 | 5.60 | 1.40–27.82 | 0.009 |
Partial gastrectomy | 12 | 1 | |||
Serosal invasion | Present | 4 | 1.17 | 0.17–4.89 | 0.841 |
Absent | 16 | 1 | |||
Lymph node metastasis | N2/N3 | 12 | 1.68 | 0.50–6.53 | 0.406 |
N0/N1 | 8 | 1 | |||
Lymphatic invasion | ly2/ly3 | 11 | 0.39 | 0.08–1.35 | 0.150 |
ly0/ly1 | 9 | 1 | |||
Venous invasion | v2/v3 | 11 | 0.57 | 0.16–1.92 | 0.354 |
v0 /v1 | 9 | 1 | |||
Number of hepatic tumors | Solitary | 11 | 0.34 | 0.08–116 | 0.077 |
Multiple | 9 | 1 | |||
Maximum size of the metastatic tumor | ≤ 3 cm | 14 | 0.41 | 0.12–1.40 | 0.197 |
> 3 cm | 6 | 1 | |||
Time of hepatectomy | Synchronous | 11 | 1.31 | 0.39–4.59 | 0.660 |
Metachronous‡ | 9 | 1 | |||
Repeat hepatectomy | Repeat | 5 | 0.81 | 0.17–2.87 | 0.758 |
Once | 15 | 1 | |||
Postoperative chemotherapy (cycle) | ≥ 3 | 11 | 0.47 | 0.13–1.57 | 0.203 |
< 3 | 9 | 1 | |||
CEA (ng/mL) | ≥ 6.0 | 6 | 5.57 | 1.34–27.79 | 0.091 |
< 6.0 | 14 | 1 | |||
CA19-9 (U/mL) | ≥ 37.0 | 4 | 7.94 | 1.42–44.33 | 0.003 |
< 37.0 | 16 | 1 | |||
AFP | Positive | 4 | 1.66 | 0.36–5.78 | 0.453 |
Negative | 16 | 1 | |||