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Table 6 Results of multivariable survival analyses for RFS according to the extended Cox regression model in cutaneous melanoma

From: Time-varying pattern of recurrence risk for localized melanoma in China

Variable

HR

95%CI of HR

P

Primary site

  

< 0.01

 CSD/non-CSD

1.46

1.20–1.79

 

 Acral

1

  

Tumor thickness

  

< 0.01

 > 4 mm

1.96

1.59–2.43

 

 ≤ 4 mm

1

  

Ulceration

  

0.005

 Present

1.32

1.09–1.61

 

 Absent

1

  

Regional lymph node metastasis

  

< 0.01

 Yes

Exp [1.906–0.519ln(t)]

  

 No

1

  

Wound infection

  

< 0.001

 Yes

2.29

1.70–3.07

 

 No

1

  

Adjuvant therapy

  

< 0.001

 Yes

0.66

0.55–0.80

 

 No

1

  
  1. CSD melanoma on skin with chronic sun-induce damage; non-CSD melanoma on skin without chronic sun-induce damage; t follow-up time after surgery