Table 1 Correlations between CBP/p300 expression and clinicopathological parameters
From: The prognostic capacities of CBP and p300 in locally advanced rectal cancer
Variable | No. of patients | CBP expression | p300 expression | p value | ||||
|---|---|---|---|---|---|---|---|---|
Low | Medium | High | Low | Medium | High | |||
Total | 93 | 28 (30.1%) | 33 (35.5%) | 32 (34.4%) | 31 (33.3%) | 30 (32.3%) | 32 (34.4%) | 0.86 |
Female | 30 | 7 (23.3%) | 11 (36.7%) | 12 (40.0%) | 7 (23.3%) | 10 (33.3%) | 13 (43.3%) | 0.96 |
Male | 63 | 21 (33.3%) | 22 (34.9%) | 20 (31.7%) | 24 (38.1%) | 20 (31.7%) | 19 (30.2%) | 0.85 |
Age (years) | ||||||||
< 60 | 68 | 25 (36.8%) | 21 (30.9%) | 22 (32.4%) | 25 (36.8%) | 19 (27.9%) | 24 (35.3%) | 0.91 |
≥ 60 | 25 | 3 (12.0%) | 12 (48.0%) | 10 (40.0%) | 6 (24.0%) | 11 (44.0%) | 8 (32.0%) | 0.53 |
Tumour infiltration | ||||||||
pT1 | 3 | 2 (66.7%) | 0 (0%) | 1 (33.3%) | 0 (0%) | 1 (33.3%) | 2 (66.6%) | 0.19 |
pT2 | 18 | 6 (33.3%) | 5 (27.8%) | 7 (38.9%) | 4 (22.2%) | 6 (33.3%) | 8 (44.4%) | 0.76 |
pT3 | 61 | 18 (29.5%) | 23 (37.7%) | 20 (32.8%) | 23 (37.7%) | 22 (36.1%) | 16 (26.2%) | 0.58 |
pT4 | 11 | 2 (18.2%) | 5 (45.5%) | 4 (36.3%) | 4 (36.4%) | 1 (9.1%) | 6 (54.5%) | 0.15 |
Lymph node status | ||||||||
pN0 | 53 | 15 (28.3%) | 18 (34.0%) | 20 (37.7%) | 16 (30.2%) | 18 (34.0%) | 19 (35.8%) | 0.97 |
pN1 | 22 | 7 (31.8%) | 9 (40.9%) | 6 (27.3%) | 8 (36.4%) | 8 (36.4%) | 6 (27.3%) | 0.94 |
pN2 | 18 | 6 (33.3%) | 6 (33.3%) | 6 (33.3%) | 7 (38.9%) | 4 (22.2%) | 7 (38.9%) | 0.76 |
Lymphatic vessel invasion | ||||||||
L0 | 68 | 20 (29.4%) | 24 (35.3%) | 24 (35.3%) | 20 (29.4%) | 24 (35.3%) | 24 (35.3%) | 1 |
L1 | 23 | 7 (30.4%) | 9 (39.1%) | 7 (30.4%) | 10 (43.5%) | 6 (26.1%) | 7 (30.4%) | 0.57 |
LX | 2 | 1 (50.0%) | 0 (0%) | 1 (50.0%) | 1 (50.0%) | 0 (0%) | 1 (50.0%) | n/a |
Vein invasion | ||||||||
V0 | 80 | 24 (30.0%) | 27 (33.8%) | 29 (36.2%) | 26 (32.5%) | 25 (31.2%) | 29 (36.2%) | 0.92 |
V1 | 12 | 4 (33.3%) | 6 (50.0%) | 2 (16.7%) | 5 (41,7%) | 5 (41.7%) | 2 (16.7%) | 0.9 |
VX | 1 | 0 (0%) | 0 (0%) | 1 (100.0%) | 0 (0%) | 0 (0%) | 1 (100%) | n/a |
Grade | ||||||||
G1 | 0 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | n/a |
G2 | 67 | 20 (30.0%) | 25 (37.2%) | 22 (32.8%) | 23 (34.3%) | 21 (31.3%) | 23 (34.3%) | 0.75 |
G3 | 25 | 8 (32.0%) | 8 (32.0%) | 9 (36.0%) | 8 (32.0%) | 9 (36.0%) | 8 (32.0%) | 0.94 |
GX | 1 | 0 (0%) | 0 (0%) | 1 (100%) | 0 (0%) | 0 (0%) | 1 (100.0%) | n/a |
Resection boundaries | ||||||||
R0 | 89 | 28 (31.5%) | 31 (34.8%) | 30 (33.7%) | 30 (33.7%) | 30 (33.7%) | 29 (32.6%) | 0.95 |
R1 | 4 | 0 (0%) | 2 (50.0%) | 2 (50.0%) | 1 (25.0%) | 0 (0%) | 3 (75.0%) | 0.2 |
UICC | ||||||||
pUICC I | 14 | 6 (42.9%) | 1 (7.1%) | 7 (50.0%) | 3 (21.4%) | 5 (35.7%) | 6 (42.9%) | 0.15 |
pUICC II | 39 | 9 (23.0%) | 17 (43.7%) | 13 (33.3%) | 13 (33.3%) | 13 (33.3%) | 13 (33.3%) | 0.53 |
pUICC III | 38 | 13 (34.2%) | 14 (36.9%) | 11 (28.9%) | 15 (39.5%) | 12 (31.6%) | 11 (28.9%) | 0.86 |
pUICC IV | 2 | 0 (0%) | 1 (50.0%) | 1 (50.0%) | 0 (0%) | 0 (0%) | 2 (100.0%) | n/a |