Skip to main content

Table 4 Multivariate analysis of prognostic factors in patients with hepatocellular carcinoma (HCC) conducted in a step-wise manner

From: Angiogenic inflammation and formation of necrosis in the tumor microenvironment influence patient survival after radical surgery for de novo hepatocellular carcinoma in non-cirrhosis

Variable Category Odds ratio p Confidence interval
Overall survival
  Distant metastases Negative (n = 47) 0.605 0.602 0.091–4.011
Positive (n = 11)    
  Overall tumor recurrence Negative (n = 35) 1.828 0.272 0.623–5.368
Positive (n = 23)    
  Angioinvasion Negative (n = 28) 0.286 0.040 0.086–0.945
Positive (n = 30)    
  Lymphangiosis carcinomatosa Negative (n = 41) 1.700 0.330 0.585–4.940
Positive (n = 17)    
  T status T1&T2 (n = 29) 18.606 0.001 3.397–101.904
T3&T4 (n = 29)   
  Angiopoietin-1 in TCA Negative (n = 55) 4.859 0.021 1.274–18.537
Positive (n = 3)    
  TEMs in TCA Negative (n = 44) 2.837 0.051 0.997–8.071
Positive (n = 14)    
Recurrence-free survival
  R status Negative (n = 49) 4.346 0.061 0.936–20.174
Positive (n = 9)    
  T status T1&T2 (n = 29) 11.213 0.0001 2.997–41.957
T3&T4 (n = 29)   
  Angioinvasion Negative (n = 28) 0.458 0.122 0.170–1.234
Positive (n = 30)    
  Lymph node involvement Negative (n = 56) 0.311 0.255 0.042–2.322
Positive (n = 56)    
  TEMs in TCA Negative (n = 44) 0.391 0.083 0.135–1.132
Positive (n = 14)    
  TEMs in TIF Negative (n = 19) 3.677 0.049 1.1007–13.430
Positive (n = 39)    
  Angiopoietin-1 in TIF Negative (n = 9) 0.102 0.001 0.028–0.380
Positive (n = 49)    
  Angiopoietin-1 in TCA Negative (n = 55) 20.920 0.004 2.620–167.067
Positive (n = 3)