Skip to main content

Table 3 Baseline characteristics related to prognosis

From: Does high-grade dysplasia/carcinoma in situ of the biliary duct margin affect the prognosis of extrahepatic cholangiocarcinoma? A meta-analysis

Outcome

Studies

Participants

Effect model

OR (95% CI)

HGD/CIS vs. R0

Adjuvant therapy

3

377

Fixed

1.55 (0.75–3.20)

Differentiation (moderate/poor)

5

660

Fixed

0.62 (0.36–1.06)

Venous invasion

3

389

Fixed

1.87 (0.83–4.21)

Perineural invasion

4

575

Fixed

1.00 (0.52–1.91)

pT 3/4*

4

494

Fixed

0.57 (0.29–1.10)

pN 1/2*

3

388

Fixed

0.52 (0.24–1.15)

HGD/CIS vs. INV

Adjuvant therapy

4

203

Fixed

0.79 (0.42–1.47)

Differentiation (moderate/poor)

5

126

Fixed

0.50 (0.23–1.08)

Venous invasion

3

76

Random

0.30 (0.02–4.07)

Perineural invasion

4

95

Fixed

0.44 (0.15–1.33)

pT 3/4*

4

102

Fixed

0.44 (0.19–1.02)

pN 1/2*

3

73

Fixed

0.62 (0.22–1.76)

  1. *According to the 8th edition American Joint Committee on Cancer (AJCC) staging guidelines