Outcome | Studies | Participants | Effect model | OR (95% CI) |
---|---|---|---|---|
HGD/CIS vs. R0 | ||||
Adjuvant therapy | 3 | 377 | Fixed | 1.55 (0.75–3.20) |
Differentiation (moderate/poor) | 5 | 660 | Fixed | 0.62 (0.36–1.06) |
Venous invasion | 3 | 389 | Fixed | 1.87 (0.83–4.21) |
Perineural invasion | 4 | 575 | Fixed | 1.00 (0.52–1.91) |
pT 3/4* | 4 | 494 | Fixed | 0.57 (0.29–1.10) |
pN 1/2* | 3 | 388 | Fixed | 0.52 (0.24–1.15) |
HGD/CIS vs. INV | ||||
Adjuvant therapy | 4 | 203 | Fixed | 0.79 (0.42–1.47) |
Differentiation (moderate/poor) | 5 | 126 | Fixed | 0.50 (0.23–1.08) |
Venous invasion | 3 | 76 | Random | 0.30 (0.02–4.07) |
Perineural invasion | 4 | 95 | Fixed | 0.44 (0.15–1.33) |
pT 3/4* | 4 | 102 | Fixed | 0.44 (0.19–1.02) |
pN 1/2* | 3 | 73 | Fixed | 0.62 (0.22–1.76) |