From: Factors predicting recurrence after curative resection for rectal cancer: a 16-year study
Without recurrence, n = 135 | Recurrence, n = 53 | Total, N = 188 | ||||
---|---|---|---|---|---|---|
N | % | N | % | N | % | |
Demographic characteristics | ||||||
Sex | ||||||
Male | 84 | 62.2 | 24 | 45.3 | 108 | 57.4 |
Female | 51 | 37.8 | 29 | 54.7 | 80 | 42.6 |
Age | ||||||
< 50 years | 23 | 17.0 | 18 | 34.0 | 41 | 21.8 |
≤ 50 years | 112 | 83.0 | 35 | 66.0 | 147 | 78.2 |
Clinical characteristics | ||||||
Location of the tumor | ||||||
Upper rectum | 36 | 26.7 | 9 | 17.0 | 45 | 23.9 |
Middle rectum | 49 | 36.3 | 16 | 30.2 | 65 | 34.6 |
Low rectum | 50 | 37.0 | 28 | 50.9 | 77 | 41.0 |
Size of the tumor | ||||||
< 5 cm | 92 | 68.1 | 24 | 45.2 | 116 | 61.7 |
> 5 cm | 43 | 31.1 | 29 | 54.8 | 72 | 38,3 |
Stenotic character | ||||||
Yes | 21 | 15 | 13 | 24.6 | 34 | 18 |
No | 114 | 85 | 40 | 75.4 | 154 | 82 |
CEA levels | ||||||
Normal | 26 | 19.2 | 24 | 45.2 | 50 | 27 |
Abnormal | 109 | 80.8 | 29 | 54.8 | 138 | 73 |
Neoadjuvant therapy | ||||||
Yes | 85 | 62.9 | 35 | 66 | 120 | 63.8 |
No | 50 | 37.1 | 18 | 34 | 68 | 36.2 |
Surgical intervention | ||||||
Abdominoperineal resection | 22 | 15.6 | 13 | 24.5 | 35 | 18.1 |
Anterior resection of the rectum | 108 | 70.4 | 36 | 67.9 | 144 | 77.1 |
Local excision | 5 | 4.4 | 4 | 7.5 | 9 | 4.8 |
Distal margin | ||||||
≤ 2 cm | 37 | 27.4 | 31 | 58.4 | 68 | 37 |
> 2 cm | 90 | 72.6 | 22 | 41.6 | 112 | 63 |
Intraoperative incident | ||||||
Yes | 32 | 23.7 | 17 | 32 | 49 | 26 |
No | 103 | 76.3 | 36 | 68 | 139 | 64 |
pT stage | ||||||
T1–T2 | 54 | 40 | 10 | 18.8 | 64 | 34 |
T3–T4 | 81 | 60 | 43 | 81.2 | 124 | 66 |
Invasion of neighboring organs | ||||||
Yes | 6 | 4 | 10 | 18.8 | 16 | 8.5 |
No | 129 | 96 | 43 | 81.2 | 172 | 11.5 |
Tumor perforation | ||||||
Yes | 2 | 1.5 | 5 | 9.4 | 7 | 3.7 |
No | 133 | 98.5 | 48 | 90.6 | 181 | 96.3 |
pN stage | ||||||
N0 | 106 | 78.5 | 21 | 39.6 | 127 | 67.5 |
N+ | 29 | 21.5 | 32 | 60.4 | 61 | 32.5 |
Extra capsular invasion | ||||||
Yes | 8 | 6 | 31 | 58.4 | 39 | 20.7 |
No | 127 | 64 | 22 | 41.6 | 149 | 79.3 |
Vascular emboli | ||||||
Yes | 10 | 7.4 | 20 | 37.7 | 30 | 16 |
No | 125 | 92.6 | 33 | 62.3 | 158 | 84 |
Lymphatic and perineural invasion | ||||||
Yes | 7 | 5.2 | 14 | 26.4 | 21 | 11.1 |
No | 128 | 94.8 | 39 | 73.6 | 167 | 88.9 |
pTNM stage | ||||||
I and II | 102 | 75.5 | 22 | 41.5 | 124 | 66 |
III and IV | 33 | 84.5 | 31 | 58.5 | 64 | 34 |