Table 1 Patients’ characteristics
Variable | Patients (n = 79) |
|---|---|
Age | |
 Median (range) | 68 (42–83) |
Sex | |
 Male | 44 (56%) |
 Female | 35 (44%) |
Type of pancreatectomy | |
 PD | 45 (57%) |
 PpPD | 31 (39%) |
 SSPPD | 3 (4%) |
Node dissection | |
 D1 | 24 (30%) |
 D2 | 52 (66%) |
 D3 | 3 (4%) |
Operative time (min) | |
 Median (range) | 466 (293–856) |
Blood loss (ml) | |
 Median (range) | 850 (100–3696) |
Transfusion | |
 Yes | 19 (24%) |
 No | 60 (76%) |
Morbidity | |
 Clavien-Dindo grade IIIa | 35 (44%) |
 Pancreatic fistula Grade B, C | 20 (25%) |
Tumor diameter (mm) | |
 Median (range) | 20 (8–65) |
Tumor ulceration | |
 Yes | 22 (28%) |
 No | 57 (72%) |
Type of adenocarcinoma | |
 Poorly differentiated | 11 (14%) |
 Moderately differentiated | 22 (28%) |
 Well differentiated | 33 (42%) |
 Papillary | 12 (15%) |
 Mucinous | 1 (1%) |
T stage (AJCC 8th) | |
 T1a | 21 (27%) |
 T1b | 16 (20%) |
 T2 | 15 (19%) |
 T3a | 27 (34%) |
N stage (AJCC 8th) | |
 N0 | 53 (67%) |
 N1 | 22 (28%) |
 N2 | 4 (5%) |
Overall stage (AJCC 8th) | |
 IA | 20 (25%) |
 IB | 18 (23%) |
 IIA | 15 (19%) |
 IIIA | 22 (28%) |
 IIIB | 4 (5%) |
HMGB1 staining intensity | |
 1 (no staining) | 14 (18%) |
 2 (light brown) | 34 (43%) |
 3 (moderate brown) | 23 (29%) |
 4 (brown or dark brown) | 8 (10%) |
HMGB1 positive cells (%) | |
 1 (0–25%) | 32 (41%) |
 2 (26–50%) | 13 (16%) |
 3 (51–75%) | 10 (13%) |
 4 (76–100%) | 24 (30%) |
HMGB1 expression | |
 High | 31 (39%) |
 Low | 48 (61%) |
Adjuvant chemotherapy | |
 Yes | 28 (35%) |
 Gem | 19 (24%) |
 S-1 | 7 (9%) |
 Others | 5 (6%) |
 No | 51 (65%) |