Table 1 Collected patient data
From: Surgery for gastrointestinal metastases of malignant melanoma — a retrospective exploratory study
No. | Gender | Age | TNM at surgery | Primary site | BRAF status | Time diagnosis to M1c | Pre-op treatment | Time M1c to surgery | Surgery | Radicality | Indication | Elective/emergency | WHO performance status | Complication (Clavien-Dindo), type | Length of stay (days) | Stay at ICU (days) | Post-op treatment | Status | Survival from surgery | Survival from M1c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Male | 63 | T0N3M1c | Unknown | V600E/K | 25 | C, I, R (lumbar spine) | 4.2 | Enterectomy + fistula and abscess | R0 | Sepsis, abscess | Emergency | 1 | II, antibiotics postop | 11 | 0 | R (brain) | DWD | 3.9 | 8.1 |
2 | Male | 73 | T3bN0M1c | Back | wt | 40 | 0 | 2.8 | Enterectomy, part. colectomy | R0 | Bleeding, anemia | Elective | 1 | 0 | 8 | 0 | R (brain) | DWD | 17.1 | 19.9 |
3 | Female | 51 | T2aN0M1c | Left leg | V600E/K | 94 | 0 | 0.5 | Enterectomy | R2 | Pain, bleeding | Elective | 1 | 0 | 7 | 0 | C, I | DWD | 14.9 | 15.4 |
4 | Male | 72 | T3bN1aM1c(0) | Back | wt | 50 | C | 4.1 | Enterectomy x 2 | R2 | Pain, anemia | Elective | 1 | I, long time to oral intake | 8 | 0 | C | AWD | 58.6 | 62.7 |
4 (2nd) | * | * | T3bN1aM1c(0) | * | wt | 50 | C | 19.1 | Enterectomy, appendectomy | R0 | Pain, anemia | Elective | 0 | 0 | 4 | 0 | I | ANED | 43.6 | 62.7 |
5 | Male | 39 | T4aN0M1c(0) | Left arm | wt | 23 | 0 | 0.8 | Enterectomy | R0 | Pain, anemia | Elective | 1 | 0 | 5 | 0 | 0 | ANED | 55.4 | 56.2 |
6 | Male | 71 | T1bN0M1c | Back | wt | 139 | 0 | 1.6 | Enterectomy x 2 | R0 | Anemia | Elective | 1 | I, bradycardia | 8 | 0 | 0 | DWD | 43.3 | 44.9 |
6 (2nd) | * | * | T1bN0M1c | * | wt | 173 | 0 | 36.8 | Part. colectomy + omentum | R0 | Anemia | Elective | 2 | IIIb, wound rupture and reoperation | 16 | 0 | 0 | DWD | 8.1 | 44.9 |
7 | Male | 68 | T0N3bM1d(0) | Unknown | wt | 4 | C | 4.6 | Enterectomy | R2 | Ileus, pain, anemia | Emergency | 1 | 0 | 9 | 0 | C | DWD | 12.8 | 17.5 |
8 | Male | 75 | T0N2cM1c(1) | Unknown | wt | 0 | C | 1.3 | Enterectomy x 2 | R2 | Small bowel perforation | Emergency | 2 | II, antibiotics postop | 25 | 1 | 0 | DWD | 1.0 | 2.3 |
9 | Female | 28 | T1aN1aM1c(1) | Back | V600E/K | 52 | C, I | 34.7 | Debulking of small bowel mesentery | R2 | Ileus, pain | Emergency | 2 | I, PCA pump | 15 | 0 | C, I | DWD | 18.5 | 53.3 |
9 (2nd) | * | * | T1bN1aM1c(1) | * | V600E/K | 52 | C, I | 46.9 | Enterectomy x 2, debulking | R2 | Pain, anemia | Emergency | 2 | I | 14 | 0 | C, I | DWD | 6.3 | 53.3 |
10 | Male | 52 | T0N2bM1c(1) | Unknown | wt | 0 | C, I, R (axilla) | 8.0 | Part. colectomy + abdominal wall | R1 | Pain | Elective | 1 | I | 8 | 0 | C, I | DWD | 13.9 | 21.9 |
11 | Male | 69 | T4bN1aM1c(1) | Back | V600E/K | 36 | 0 | 1.5 | Enterectomy x 2 | R2 | Anemia, bleeding | Elective | 3 | I | 21 | 0 | I | DWD | 3.8 | 5.3 |
12 | Male | 52 | T4bN2M1c(0) | Right temple | wt | 3 | C, I | 37.7 | Enterectomy | R0 | Anemia | Elective | 0 | 0 | 6 | 0 | I | ANED | 16.7 | 54.5 |
13 | Female | 58 | T3aN3bM1c(1) | Right arm | V600E/K | 63 | C, ILP, I | 46.0 | Enterectomy | R0 | Ileus, pain, anemia, bleeding | Emergency | 3 | 0 | 13 | 0 | C | DWD | 13.7 | 59.7 |
14 | Male | 63 | T4bN0M1c(0) | Right leg | wt | 84 | C, I, R (lung) | 0.8 | Enterectomy | R0 | Anemia, bleeding | Elective | 1 | I, gastric retention | 7 | 0 | C, I | AWD | 11.3 | 12.1 |
15 | Male | 67 | T1aN2bM1c(0) | Thorax | V600E/K | 14 | R (axilla) | 3.1 | Enterectomy + omentum | R0 | Anemia, bleeding | Elective | 1 | II, blood transfusion | 5 | 0 | 0 | ANED | 2.9 | 6.0 |