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Table 1 Summary of the cases

From: Hepatectomy for metachronous colorectal liver metastases following complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal metastases: a report of three cases

 

Case 1

Case 2

Case3

Site of the primary tumor

Ascending colon

Cecum

Sigmoid colon

Time from the primary tumor resection to peritoneal metastases (month)

26

12

Simultaneous

Time from the primary tumor resection to CRS and HIPEC (month)

32

17

13

Adjuvant chemotherapy after CRS and HIPEC

None

None

5-FU + LV + bevacizumab

8 cycles

Time from CRS + HIPEC to liver metastases (month)

15

5

6

Chemotherapy before hepatectomy

IRIS + bevacizumab

12 cycles

FOLFOX + bevacizumab

5 cycles

–

Time from CRS + HIPEC to hepatectomy (month)

49

9

6

Operative procedure of hepatectomy

Left hemihepatectomy

Partial resection of S5

Posterior sectionectomy

Left lateral sectionectomy

Partial resection of S5 and S8

Operative time (min)

269

150

335

Blood loss (ml)

530

233

250

Complications after hepatectomy

Chylous ascites

None

None

Clinical outcome

No recurrence

No recurrence

Death in 16 months after hepatectomy

  1. Abbreviations: CRC colorectal cancer, CRS cytoreductive surgery, HIPEC hyperthermic intraperitoneal chemotherapy, S segment