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Table 2 Multiple logistic regression analysis of clinical and pathological factors that can be predictors of lymph node metastasis (pN0/pN1, 0/1) in the patients with PTMC. Results were also confirmed by chi-square test

From: Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”?

Variables Patients with pN0 (n = 115) Patients with pN1 (n = 62) P value (χ2 test) Logistic regression analysis
OR ± 95% CI P value (Wald test)
N (%) N (%)
Gender   0.065 0.93 0.42–2.06 0.858
 Male 11 (9.6) 12 (19.3)  
 Female 104 (90.4) 50 (80.7)  
Age    0.303 0.96 0.51–1.80 0.890
 < 55 years 74 (64.4) 35 (56.5)  
 ≥ 55 years 41 (35.6) 27 (43.5)  
Diagnosed as multifocal    < 0.0001* 9.40 4.6–19.3 < 0.0001*
 No 94 (81.7) 20 (32.3)  
 Yes 21 (18.3) 42 (67.7)  
Diagnosed as bilateral   < 0.0001* 2.90 0.0–12.8 < 0.0001*
 No 115 (100.0) 47 (75.8)  
 Yes 0 (0.0) 15 (24.2)  
Tumor size   < 0.0001* 65.80 15.1–287.3 < 0.0001*
 < 0.5 cm 79 (68.7) 2 (3.2)  
 ≥ 0.5 cm 36 (31.3) 60 (96.8)  
Capsular invasion   0.047 2.54 0.98–6.56 0.052
 No 106 (92.2) 51 (82.3)  
 Yes 9 (7.8) 11 (17.7)  
  1. PTMC papillary thyroid microcarcinoma, CI coefficient interval, *statistically significant