Table 2 Multiple logistic regression analysis of clinical and pathological factors that can be predictors of lymph node metastasis (pN0/pN1, 0/1) in the patients with PTMC. Results were also confirmed by chi-square test
From: Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”?
Variables | Patients with pN0 (n = 115) | Patients with pN1 (n = 62) | P value (χ2 test) | Logistic regression analysis | ||
|---|---|---|---|---|---|---|
OR | ± 95% CI | P value (Wald test) | ||||
N (%) | N (%) | |||||
Gender | 0.065 | 0.93 | 0.42–2.06 | 0.858 | ||
Male | 11 (9.6) | 12 (19.3) | ||||
Female | 104 (90.4) | 50 (80.7) | ||||
Age | 0.303 | 0.96 | 0.51–1.80 | 0.890 | ||
< 55 years | 74 (64.4) | 35 (56.5) | ||||
≥ 55 years | 41 (35.6) | 27 (43.5) | ||||
Diagnosed as multifocal | < 0.0001* | 9.40 | 4.6–19.3 | < 0.0001* | ||
No | 94 (81.7) | 20 (32.3) | ||||
Yes | 21 (18.3) | 42 (67.7) | ||||
Diagnosed as bilateral | < 0.0001* | 2.90 | 0.0–12.8 | < 0.0001* | ||
No | 115 (100.0) | 47 (75.8) | ||||
Yes | 0 (0.0) | 15 (24.2) | ||||
Tumor size | < 0.0001* | 65.80 | 15.1–287.3 | < 0.0001* | ||
< 0.5 cm | 79 (68.7) | 2 (3.2) | ||||
≥ 0.5 cm | 36 (31.3) | 60 (96.8) | ||||
Capsular invasion | 0.047 | 2.54 | 0.98–6.56 | 0.052 | ||
No | 106 (92.2) | 51 (82.3) | ||||
Yes | 9 (7.8) | 11 (17.7) | ||||