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Table 5 Summary of subgroup analyses: MWA vs. HR

From: Microwave ablation compared with hepatic resection for the treatment of hepatocellular carcinoma and liver metastases: a systematic review and meta-analysis

Subgroup LTR [RR (95% CI); P value; studies (N); I2] OS (1-year) [RR (95% CI); P value; studies (N); I2] Complications [RR (95% CI); P value; studies (N); I2]
Tumor size
 < 3 cm 2.93 (1.26, 6.81); P = 0.013; 4; 64% 1.01 (0.99, 1.04); P = 0.41; 3; 0% 0.57 (0.06, 5.05); P = 0.615; 3; 67%
 ≥ 3 cm 1.24 (0.53, 2.88); P = 0.624; 2; 62% 0.96 (0.88, 1.04); P = 0.329; 3; 0% 0.30 (0.14, 0.64); P = 0.002; 2; 0%
Type of tumor    
 HCC 3.04 (1.84, 5.02); P < 0.001; 7; 32% 1.01 (0.99, 1.03); P = 0.311; 7; 0% 0.36 (0.19, 0.66); P = 0.001; 6; 21%
 Liver metastases Too few studies (< 2) to inform 0.96 (0.88, 1.06); P = 0.451; 3; 0% 0.22 (0.09, 0.56); P = 0.001; 2; 0%
MWA frequency
 2450 MHz 2.35 (1.49, 3.70); P < 0.001; 6; 0% 1.00 (0.98, 1.03); P = 0.766; 8; 0% 0.35 (0.18, 0.68); P = 0.002; 6; 31%
 915 MHz 2.44 (0.31, 19.10); P = 0.396; 2; 96% 0.98 (0.84, 1.14); P = 0.77; 2; 83% 0.24 (0.10, 0.61); P = 0.002; 2; 0%
  1. Italicized values indicate statistical significance. Point estimates and confidence intervals were calculated using a random effects model
  2. Abbreviations: CI confidence interval, HCC hepatocellular carcinoma, LTR local tumor recurrence, MWA microwave ablation, OS overall survival, RR risk ratio