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Table 1 Baseline characteristics

From: Validation of the Toronto hepatocellular carcinoma risk index for patients with cirrhosis in China: a retrospective cohort study

 

All patients (n = 520)

HCC (n = 76)

Non-HCC (n = 444)

p value (HCC vs. non-HCC)

Mean age ± SD, years

60.46 ± 12.95 (24–89)

59.76 ± 11.67 (36–84)

60.58 ± 13.16 (24–89)

0.613

Sex

   

0.000

 Female, n (%)

219 (42)

16 (21)

203 (46)

 

 Male, n (%)

301 (58)

60 (79)

241 (54)

 

Mean follow-up ± SD, months

32.48 ± 23.22

39.57 ± 25.90

31.27 ± 22.54

0.004

Median follow-up (range), months

26.86 (6.18–109.48)

32.30 (6.77–104.02)

25.59 (6.18–109.48)

 

Etiology, n (%)

   

0.000

 HBV

184 (35)

46 (61)

138 (31)

 

 HCV

8 (2)

3 (4)

5 (1)

 

 ALD

30 (6)

6 (8)

24 (5)

 

 NAFLD

1 (0)

0 (0)

1 (0)

 

 AIH

33 (6)

2 (3)

31 (7)

 

 PBC

23 (4)

0 (0)

23 (5)

 

 PSC

1 (0)

0 (0)

1 (0)

 

 OTHER

240 (46)

19 (25)

221 (50)

 

Mean BMI ± SD, kg/m2

23.27 ± 3.44

23.68 ± 3.13

23.18 ± 3.51

0.359

Mean PLT ± SD, 10E9/L

99.86 ± 69.27

87.99 ± 66.83

101.90 ± 69.55

0.106

Mean INR ± SD

1.28 ± 0.39

1.31 ± 0.23

1.27 ± 0.41

0.512

Mean PT ± SD, sec

14.96 ± 4.98

15.44 ± 2.70

14.87 ± 5.28

0.396

Mean ALT ± SD, U/L

60.49 ± 152.66

61.44 ± 161.54

60.32 ± 151.29

0.954

Mean AST ± SD, U/L

68.15 ± 124.32

65.24 ± 97.63

68.66 ± 128.45

0.826

Mean GGT ± SD, U/L

113.52 ± 141.60

89.04 ± 90.89

117.81 ± 148.37

0.107

Mean ALB ± SD, g/L

33.09 ± 6.33

33.00 ± 6.01

33.10 ± 6.39

0.897

Mean TBil ± SD, μmol/L

38.98 ± 48.44

35.24 ± 30.86

39.61 ± 50.81

0.476

Mean Cr ± SD, μmol/L

75.08 ± 54.49

73.65 ± 33.97

75.31 ± 57.16

0.816

Mean AFP ± SD, μg/L

14.38 ± 59.90

24.85 ± 51.65

12.31 ± 61.29

0.227

Mean THRI ± SD

239.17 ± 68.21

279.49 ± 57.07

232.27 ± 67.62

0.000

Mean APRI ± SD

2.40 ± 4.07

3.04 ± 7.65

2.29 ± 3.06

0.138

Mean FIB-4 ± SD

7.71 ± 6.31

8.58 ± 6.44

7.56 ± 6.28

0.197

Mean MELD ± SD

7.57 ± 5.99

7.81 ± 6.53

7.53 ± 5.90

0.731

Mean Child-Pugh Score ± SD

7.15 ± 1.74

7.28 ± 2.09

7.13 ± 1.67

0.545

  1. SD standard deviation, HBV hepatitis B virus, HCV hepatitis C virus, ALD alcohol liver disease, NAFLD non-alcoholic fatty liver disease, AIH autoimmune hepatitis, PBC primary biliary cirrhosis, PSC primary sclerosing cholangitis, BMI body mass index, PLT platelet count, PT prothrombin time, INR international normalized ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyl transpeptidase, ALB albumin, TBil total bilirubin, Cr creatinine, AFP alpha fetoprotein, THRI Toronto hepatocellular carcinoma risk index, APRI AST to platelet ratio index, FIB-4 Fibrosis-4 score, MELD model for end-stage liver disease
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World Journal of Surgical Oncology

ISSN: 1477-7819

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