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Table 3 Univariate and multivariate analysis for overall survival

From: Peritoneal carcinomatosis index predicts survival in colorectal patients undergoing HIPEC using oxaliplatin: a retrospective single-arm cohort study

Covariates

Univariate analysis

Multivariate analysis

 

HR

95% CI

p value

HR

95% CI

p value

Age

0.991

(0.951–1.032)

0.659

   

Female

Ref

     

Male

2.152

(0.974–4.751)

0.058

   

Colon primary

Ref

     

Rectal primary

1.268

(0.436–3.689)

0.663

   

Classic adenocarcinoma

Ref

     

Mucinous adenocarcinoma

1.037

(0.415–2.589)

0.938

   

Grade I (histology)

Ref

     

Grade II (histology)

0.845

(0.331–2.156)

0.725

   

Grade III (histology)

0.889

(0.309–2.562)

0.828

   

Presenting stage I–III

Ref

     

Presenting stage IV

1.116

(0.367–3.395)

0.846

   

Metachronous

Ref

     

Synchronous

1.028

(0.471–2.245)

0.945

   

Peri-op chemo

0.5350

(0.159–1.8)

0.788

   

Intra-op IV chemo

0.8957

(0.402–1.997)

0.697

   

PCI (continuous)

1.134

(1.074–1.198)

< 0.001

1.178

(1.083–1.281)

0.0001

Operative time (hours)

1.198

(1.012–1.417)

0.0355

0.772

(0.5493–1.086)

0.1375

Blood loss (100 ml)

1.039

(1.005–1.076)

0.0263

1.004

(0.947–1.064)

0.889

No complications

Ref

     

Grade I (complication)

2.0827

(0.704–6.247)

0.187

2.173

(0.713–6.624)

0.172

Grade II (complication)

1.692

(0.422–6.775)

0.457

3.292

(0.749–14.48)

0.114

Grade III (complication)

7.242

(2.229–24.73)

0.0012

6.324

(1.383–28.919)

0.0174

Grade IV (complication)

6.852

(1.905–52.42)

0.003

5.588

(1.256–24.865)

0.0238

  1. Boldface font indicate statistically significant p values of less than 0.05