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Table 4 Risk factors for DFS at the univariate analysis (n = 47 patients)

From: Clinicopathological characteristics and risk factors for recurrence of well-differentiated pancreatic neuroendocrine tumors after radical surgery: a case-control study

 

Log-rank

COX regression

3-year non-recurrent rate %

P

P

Exp(B) (95% CI)

Age

 50 years

46.6

0.346

0.353

0.604(0.208–1.753)

< 50 years

50.1

Gender

Male

49.2

0.862

0.863

0.908(0.301–2.743)

Female

47.5

Tumor function

Functional

80.0

0.197

0.226

0.280(0.036–2.198)

Non-functional

41.6

Surgical type

Pancreatico

-duodenectomy

26.3

0.031

0.055

0.481(0.227–1.016)

Pancreatic body and tail resection

32.0

Local resection

100

Tumor location

Body and tail

28.3

0.693

0.422

0.824(0.514–1.322)

Head

39.7

Body

100

Tail

77.8

Tumor size

 2 cm

33.5

0.078

0.274

28.199(0.071–11218.74)

< 2 cm

100

Tumor size

 4 cm

38.9

0.376

0.384

1.689(0.518–5.503)

< 4 cm

58.5

Stage

IA

100

0.008

0.007

3.081(1.366–6.947)

IB

87.5

IIA

64.3

IIB

0

Grade

G1

75

0.029

0.061

7.011(0.917–53.608)

G2

38.6

Ki-67

 10%

19.4

0.000

0.003

7.585(2.018–28.5)

< 10%

54.9

Ki-67

 5%

38.1

0.038

0.053

3.538(0.986–12.695)

< 5%

60.6

Lymph nodes status

Positive

17.0

0.210

0.221

0.516(0.179–1.490)

Negative

58.5

Vascular invasion

Positive

15.2

0.024

0.032

0.305(0.103–0.905)

Negative

54.1

Perineural invasion

Positive

0

0.073

0.087

0.36(0.112–1.159)

Negative

56.6

Margin status, n (%)

Positive

15.6

0.029

0.039

3.057(1.057–8.840)

Negative

56.2

Localized or regional stage tumors

Regional

20.0

0.007

0.018

0.165(0.037–0.734)

Localized

85.7