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Table 4 Risk factors for DFS at the univariate analysis (n = 47 patients)

From: Clinicopathological characteristics and risk factors for recurrence of well-differentiated pancreatic neuroendocrine tumors after radical surgery: a case-control study

  Log-rank COX regression
3-year non-recurrent rate % P P Exp(B) (95% CI)
Age  50 years 46.6 0.346 0.353 0.604(0.208–1.753)
< 50 years 50.1
Gender Male 49.2 0.862 0.863 0.908(0.301–2.743)
Female 47.5
Tumor function Functional 80.0 0.197 0.226 0.280(0.036–2.198)
Non-functional 41.6
Surgical type Pancreatico -duodenectomy 26.3 0.031 0.055 0.481(0.227–1.016)
Pancreatic body and tail resection 32.0
Local resection 100
Tumor location Body and tail 28.3 0.693 0.422 0.824(0.514–1.322)
Head 39.7
Body 100
Tail 77.8
Tumor size  2 cm 33.5 0.078 0.274 28.199(0.071–11218.74)
< 2 cm 100
Tumor size  4 cm 38.9 0.376 0.384 1.689(0.518–5.503)
< 4 cm 58.5
Stage IA 100 0.008 0.007 3.081(1.366–6.947)
IB 87.5
IIA 64.3
IIB 0
Grade G1 75 0.029 0.061 7.011(0.917–53.608)
G2 38.6
Ki-67  10% 19.4 0.000 0.003 7.585(2.018–28.5)
< 10% 54.9
Ki-67  5% 38.1 0.038 0.053 3.538(0.986–12.695)
< 5% 60.6
Lymph nodes status Positive 17.0 0.210 0.221 0.516(0.179–1.490)
Negative 58.5
Vascular invasion Positive 15.2 0.024 0.032 0.305(0.103–0.905)
Negative 54.1
Perineural invasion Positive 0 0.073 0.087 0.36(0.112–1.159)
Negative 56.6
Margin status, n (%) Positive 15.6 0.029 0.039 3.057(1.057–8.840)
Negative 56.2
Localized or regional stage tumors Regional 20.0 0.007 0.018 0.165(0.037–0.734)
Localized 85.7